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抑制剂激活剂等> MAPK与PI3K/Akt通路> p38 MAPK Signaling
SB203580 (p38 MAPK抑制剂)
产品编号: S1863-100mg
产品包装:100mg
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价格: ¥ 2718.00
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产品编号 产品名称 产品包装 产品价格
S1863-1mg SB203580 (p38 MAPK抑制剂) 20mg/ml×0.05ml 452.00元
S1863-5mg SB203580 (p38 MAPK抑制剂) 5mg 679.00元
S1863-25mg SB203580 (p38 MAPK抑制剂) 25mg 1225.00元
S1863-100mg SB203580 (p38 MAPK抑制剂) 100mg 2718.00元

SB203580也写作SB 203580或SB-203580,是一种常用的p38 MAPK抑制剂。SB203580可以通透细胞,抑制p38 MAPK (p38 MAP kinase),抑制后续MAPKAP Kinase-2和MAPKAP Kinase-3的激活。通过抑制p38 MAPK,SB203580可以有效抑制一些炎症因子(如IL-1β、TNF-α)诱导的部分信号转导。SB203580选择性抑制p38 MAPK,IC50为600 nM;对于JNK/SAPK和p44/42 MAPK (即Erk1/2)无显著的抑制作用,IC50仅为100 μM。
SB203580分子量为377.43,分子式为C21H16N3FOS,CAS Number:152121-47-6。本产品纯度大于99%。
本SB203580为进口分装,其中20mg/ml包装产品用DMSO配制,共0.05ml。5mg,25mg和100mg包装为粉末装。
包装清单:

产品编号 产品名称 包装
S1863-1mg SB203580 (p38 MAPK抑制剂) 20mg/ml×0.05ml
S1863-5mg SB203580 (p38 MAPK抑制剂) 5mg
S1863-25mg SB203580 (p38 MAPK抑制剂) 25mg
S1863-100mg SB203580 (p38 MAPK抑制剂) 100mg
说明书 1份

保存条件:
-20℃避光保存,一年有效。
注意事项:
本产品对人体有刺激性,操作时请小心,并注意适当防护以避免直接接触人体或吸入体内。
本SB203580在4℃、冰浴等较低温度情况下会凝固而粘在离心管管底、管壁或管盖内,可以20-25℃水浴温育片刻至全部融解后使用。
本产品仅限于专业人员的科学研究用,不得用于临床诊断或治疗,不得用于食品或药品,不得存放于普通住宅内。
为了您的安全和健康,请穿实验服并戴一次性手套操作。

使用说明:
1. SB203580常见使用浓度范围为1-50μM。具体的最佳工作浓度请参考相关文献,或根据实验目的,以及所培养的特定细胞和组织,通过实验进行摸索和优化。

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