产品编号 | 产品名称 | 产品包装 | 产品价格 |
SM2143-10mM | 槲皮苷(98%, HPLC) | 10mM×0.2ml | 113.00元 |
SM2143-5mg | 槲皮苷(98%, HPLC) | 5mg | 101.00元 |
SM2143-25mg | 槲皮苷(98%, HPLC) | 25mg | 420.00元 |
SM2143-100mg | 槲皮苷(98%, HPLC) | 100mg | 1428.00元 |
化学信息:
中文名 | 槲皮苷 |
英文名 | Quercitrin |
中文别名 | 槲皮甙;橡皮甙;榭黄甙;栎素 |
英文别名 | 3-rhamnosyl quercetin; Quercitroside; Quercitronic acid; Thujin; Quercetin 3-rhamnoside |
来源 | 合欢Albizia julibrissin Durazz.;地耳草Hypericum japonicum Thunb. ex Murray |
化合物类型 | 黄酮类(Flavonoids)>黄酮>黄酮醇 |
化学式 | C21H20O11 |
分子量 | 448.38 |
CAS号 | 522-12-3 |
纯度 | 98%, HPLC |
溶剂/溶解度 | DMSO: ≥ 31 mg/ml (69.14 mM) |
溶液配制 | 10mg加入1.12ml DMSO,或者每4.48mg加入1ml DMSO,配制成10mM溶液。 |
生物信息
产品描述 | Quercitrin is a natural compound found in Tartary buckwheat with a potential anti-inflammation effect that is used to treat heart and vascular conditions. | ||||
信号通路 | Inflammation | ||||
靶点 | Caspase-3 | MMP | - | - | - |
IC50 | - | - | - | - | - |
体外研究 | There were significant increases in caspase-3 activity, loss of MMP, and increases in the apoptotic cell population in response to quercitrin in DLD-1 colon cancer cells in a time- and dose-dependent manner. | ||||
体内研究 | ICR mice received CCl4 intraperitoneally with or without quercitrin co-administration for 4 weeks. Data showed that quercitrin significantly suppressed the elevation of reactive oxygen species (ROS) production and malondialdehyde (MDA) content, reduced tissue plasminogen activator (t-PA) activity, enhanced the antioxidant enzyme activities and abrogated cytochrome P450 2E1 (CYP2E1) induction in mouse brains. | ||||
临床实验 | N/A |
1. Cincin ZB, et al. Pathol Oncol Res. 2015,21(2):333-8.
2. Ma JQ, et al. Food Funct. 2016,7(1):549-56.
3. Li W, et al. Am J Physiol Renal Physiol. 2016,311(1):F217-26.
包装清单:产品编号 | 产品名称 | 包装 |
SM2143-10mM | 槲皮苷(98%, HPLC) | 10mM×0.2ml |
SM2143-5mg | 槲皮苷(98%, HPLC) | 5mg |
SM2143-25mg | 槲皮苷(98%, HPLC) | 25mg |
SM2143-100mg | 槲皮苷(98%, HPLC) | 100mg |
- | 说明书 | 1份 |
-20℃避光保存,至少一年有效。固体粉末4℃避光保存,至少一个月有效。如果溶于非DMSO溶剂,建议分装后-80℃避光保存,预计6个月内有效。
注意事项:本产品可能对人体有一定的毒害作用,请注意适当防护,以避免直接接触人体或吸入体内。
本产品仅限于专业人员的科学研究用,不得用于临床诊断或治疗,不得用于食品或药品,不得存放于普通住宅内。
为了您的安全和健康,请穿实验服并戴一次性手套操作。