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| 产品编号 | 产品名称 | 产品包装 | 产品价格 |
| SM5100-10mM | 京尼平苷酸(98%, HPLC) | 10mM×0.2ml | 98.00元 |
| SM5100-5mg | 京尼平苷酸(98%, HPLC) | 5mg | 83.00元 |
| SM5100-25mg | 京尼平苷酸(98%, HPLC) | 25mg | 345.00元 |
| SM5100-100mg | 京尼平苷酸(98%, HPLC) | 100mg | 1173.00元 |
化学信息：
| 中文名 | 京尼平苷酸 |
| 英文名 | Geniposidic acid |
| 中文别名 | 栀子酸；京尼平甙酸；栀子苷酸 |
| 英文别名 | Premnosidic acid |
| 来源 | 车前Plantago asiatica L.；平车前Plantago depressa Willd. |
| 化合物类型 | 萜类(Terpenoids)>单萜>环烯醚萜苷 |
| 化学式 | C16H22O10 |
| 分子量 | 374.34 |
| CAS号 | 27741-01-1 |
| 纯度 | 98%, HPLC |
| 溶剂/溶解度 | DMSO: ≥ 100 mg/ml (267.14 mM) |
| 溶液配制 | 5mg加入1.34ml DMSO，或者每3.74mg加入1ml DMSO，配制成10mM溶液。 |
生物信息
| 产品描述 | Geniposidic acid is an effective anticancer and radioprotection agent. | ||||
| 信号通路 | Apoptosis | ||||
| 靶点 | - | - | - | - | - |
| IC50 | - | - | - | - | - |
| 体外研究 | N/A | ||||
| 体内研究 | Mice were given an intraperitoneal injection of Geniposidic acid (GA) (12.5, 25, 50 mg/kg) 1 h before receiving GA against d-galactosamine (GalN) (800 mg/kg)/LPS (40 μg/kg). Liver and blood samples were collected 1 and 8 h after GalN/LPS injection. The survival rate of the GA group was significantly higher than the control. GalN/LPS increased serum aminotransferase activity, serum tumor necrosis factor-α level and hepatic lipid peroxidation and decreased hepatic glutathione content. GA enhanced significantly the postirradiation responses of splenic blastogenesis by PHA. In addition, GA is a potent tumor growth inhibitor when combined with the X-irradiation, though there was no significant synergetic effect on their combined antitumor activity. The preliminary results of GA on hematological and blastogenic observations in this study suggested that it may very well, partially, play a role in an effective anticancer product with the ability to decrease undesirable radiation damage to the hematologic tissue after high dose irradiation. | ||||
| 临床实验 | N/A | ||||
1. Kim SJ, et al. J Ethnopharmacol. 2013,146(1):271-7.
2. Hsu HY, et al. Cancer Lett. 1997,113(1-2):31-7.
包装清单：| 产品编号 | 产品名称 | 包装 |
| SM5100-10mM | 京尼平苷酸(98%, HPLC) | 10mM×0.2ml |
| SM5100-5mg | 京尼平苷酸(98%, HPLC) | 5mg |
| SM5100-25mg | 京尼平苷酸(98%, HPLC) | 25mg |
| SM5100-100mg | 京尼平苷酸(98%, HPLC) | 100mg |
| - | 说明书 | 1份 |
-20℃保存，至少一年有效。固体粉末4℃保存，至少一个月有效。如果溶于非DMSO溶剂，建议分装后-80℃保存，预计6个月内有效。
注意事项：本产品可能对人体有一定的毒害作用，请注意适当防护，以避免直接接触人体或吸入体内。
本产品仅限于专业人员的科学研究用，不得用于临床诊断或治疗，不得用于食品或药品，不得存放于普通住宅内。
为了您的安全和健康，请穿实验服并戴一次性手套操作。
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