SB203580(p38 MAPK抑制剂)

 产品编号: S1863
 产品包装: 1mg
 产品价格: 528.00元
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产品简介

产品简介:

产品编号 产品名称 产品包装 产品价格
S1863 SB203580(p38 MAPK抑制剂) 1mg 528.00元

    SB203580也写作SB 203580或SB-203580,是一种常用的p38 MAPK抑制剂。SB203580可以通透细胞,抑制p38 MAPK(p38 MAP kinase),抑制后续MAPKAP Kinase-2和MAPKAP Kinase-3的激活。通过抑制p38 MAPK,SB203580可以有效抑制一些炎症因子(如IL-1β、TNF-α)诱导的部分信号转导。SB203580选择性抑制p38 MAPK,IC50为600 nM;对于JNK/SAPK和p44/42 MAPK(即Erk1/2)无显著的抑制作用,IC50仅为100 μM。
    SB203580分子量为377.43,分子式为C21H16N3FOS,CAS Number:152121-47-6。本产品纯度大于99%。
    本SB203580为进口分装,用DMSO配制,浓度为20mg/ml,共50μl。
包装清单:

产品编号

产品名称

包装

S1863

SB203580(p38 MAPK抑制剂, 20mg/ml)

1mg

说明书

1份

保存条件:
    -20℃避光保存,一年有效。
注意事项:
    本产品对人体有刺激性,操作时请小心,并注意适当防护以避免直接接触人体或吸入体内。
    本SB203580在4℃、冰浴等较低温度情况下会凝固而粘在离心管管底、管壁或管盖内,可以20-25℃水浴温育片刻至全部融解后使用。
    为了您的安全和健康,请穿实验服并戴一次性手套操作。

使用说明

使用说明:
1. SB203580常见使用浓度范围为1-50μM。具体的最佳工作浓度请参考相关文献,或根据实验目的,以及所
   培养的特定细胞和组织,通过实验进行摸索和优化。

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