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| 产品编号 | 产品名称 | 产品包装 | 产品价格 |
| SM6068-10mM | α-常春藤皂苷(98%, HPLC) | 10mM×0.2ml | 200.00元 |
| SM6068-5mg | α-常春藤皂苷(98%, HPLC) | 5mg | 172.00元 |
| SM6068-25mg | α-常春藤皂苷(98%, HPLC) | 25mg | 715.00元 |
| SM6068-100mg | α-常春藤皂苷(98%, HPLC) | 100mg | 2431.00元 |
化学信息：
| 中文名 | α-常春藤皂苷 |
| 英文名 | Alpha-hederin |
| 中文别名 | - |
| 英文别名 | Hederin; Koronaroside A; Sapindoside A; Kalopanaxsaponin A; Kizutasaponin K6; Akebiasaponin PD; Prosapogenin CP3b; Hederoside B; Nepalin 2; Tauroside E; Calopanaxsaponin A; Helixin; Dipscacobioside; Cephalaroside C; Dipsacoside A |
| 来源 | 常春藤Hedera nepalensis var. sinensis (Tobl.) Rehd；木通Akebia quinata (Thunb.) Decne；三叶木通Akebia trifoliata (Thunb.) Koidz. |
| 化合物类型 | 萜类(Terpenoids)>三萜>齐墩果烷型五环三萜皂苷 |
| 化学式 | C41H66O12 |
| 分子量 | 750.96 |
| CAS号 | 27013-91-8 |
| 纯度 | 98%, HPLC |
| 溶剂/溶解度 | Water: < 0.1 mg/ml (insoluble); DMSO: ≥ 100 mg/ml (133.16 mM) |
| 溶液配制 | 10mg加入1.33ml DMSO，或者每7.51mg加入1ml DMSO，配制成10mM溶液。 |
生物信息
| 产品描述 | alpha-Hederin (α-Hederin), a monodesmosidic triterpenoid saponin, exhibits promising antitumor potential against a variety of human cancer cell lines. alpha-Hederin could inhibit the proliferation and induce apoptosis of gastric cancer accompanied by glutathione decrement and reactive oxygen species generation via activating mitochondrial dependent pathway. | ||||
| 信号通路 | Apoptosis; Inflammation | ||||
| 靶点 | - | - | - | - | - |
| IC50 | - | - | - | - | - |
| 体外研究 | alpha-Hederin (α-Hederin) is cytotoxic and inhibits proliferation in both cel lines at rather low concentrations. alpha-Hederin (α-Hederin)reduces the mitotic activity in treated cells. | ||||
| 体内研究 | alpha-Hederin (α-Hederin) has preventive effect on sensitized rats like thymoquinone. It may intervene in miRNA-126 expression, which consequently could interfere with IL-13 secretion pathway leading to a reduction in inflammatory responses. | ||||
| 临床实验 | N/A | ||||
1. Wang J, et al. Phytother Res. 2020,34(3):601-611.
2. Danloy S et al. Planta Med, 1994,60(1):45-9.
3. Maryam Fallahi et al. Planta Med, 1994,60(1):45-9.
包装清单：| 产品编号 | 产品名称 | 包装 |
| SM6068-10mM | α-常春藤皂苷(98%, HPLC) | 10mM×0.2ml |
| SM6068-5mg | α-常春藤皂苷(98%, HPLC) | 5mg |
| SM6068-25mg | α-常春藤皂苷(98%, HPLC) | 25mg |
| SM6068-100mg | α-常春藤皂苷(98%, HPLC) | 100mg |
| - | 说明书 | 1份 |
-20℃避光保存，至少一年有效。固体粉末4℃避光保存，至少一个月有效。如果溶于非DMSO溶剂，建议分装后-80℃避光保存，预计6个月内有效。
注意事项：本产品可能对人体有一定的毒害作用，请注意适当防护，以避免直接接触人体或吸入体内。
本产品仅限于专业人员的科学研究用，不得用于临床诊断或治疗，不得用于食品或药品，不得存放于普通住宅内。
为了您的安全和健康，请穿实验服并戴一次性手套操作。
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