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| 产品编号 | 产品名称 | 产品包装 | 产品价格 |
| SM9024-10mM | 苦杏仁苷(98%, HPLC) | 10mM×0.2ml | 76.00元 |
| SM9024-25mg | 苦杏仁苷(98%, HPLC) | 25mg | 84.00元 |
| SM9024-100mg | 苦杏仁苷(98%, HPLC) | 100mg | 286.00元 |
| 中文名 | 苦杏仁苷 |
| 英文名 | Amygdalin |
| 中文别名 | 扁桃苷；苦杏仁素；杏仁素；苦杏仁甙 |
| 英文别名 | Amygdaloside; Mandelonitrile gentiobioside; Glucoprunasin; Laetrile; Vitamin B17 |
| 来源 | 山杏Armeniaca sibirica (L.) Lam |
| 化合物类型 | 氰苷(Cyanophoric glycosides) |
| 化学式 | C20H27NO11 |
| 分子量 | 457.43 |
| CAS号 | 29883-15-6 |
| 纯度 | 98%, HPLC |
| 溶剂/溶解度 | DMSO: ≥ 75 mg/ml (163.96 mM) |
| 溶液配制 | 5mg加入1.09ml DMSO，或者每4.57mg加入1ml DMSO，配制成10mM溶液。 |
| 产品描述 | Amygdalin is a plant glucoside isolated from the stones of rosaceous fruits, such as apricots, peaches, almond, cherries, and plums. | ||||
| 信号通路 | Apoptosis | ||||
| 靶点 | - | - | - | - | - |
| IC50 | - | - | - | - | - |
| 体外研究 | Amygdalin has antitumor activity. Some advances had been made on the antitumor mechanism of amygdalin. Amygdalin downregulates especially genes belonging to cell cycle category: exonuclease 1, ATP-binding cassette, sub-family F, member 2, MRE11 meiotic recombination 11 homolog A, topoisomerase (DNA) I, and FK506 binding protein 12-rapamycin-associated protein 1. RT-PCR analysis reveals that mRNA levels of these genes are also decreased by amygdalin treatment in SNU-C4 human colon cancer cells. | ||||
| 体内研究 | Amygdalin is effective at alleviating inflammatory pain and that it can be used as an analgesic with anti-nociceptive and anti-inflammatory activities. The intramuscular injection of amygdalin significantly reduced the formalin-induced tonic pain in both early (the initial 10 min after formalin injection) and late phases (10-30 min following the initial formalin injection). During the late phase, amygdalin reduces the formalin-induced pain in a dose-dependent manner in a dose range less than 1 mg/kg. | ||||
| 临床实验 | N/A | ||||
1.Song Z, et al. J Cancer Res Ther. 2014,10 Suppl 1:3-7.
2.Park HJ,et al. World J Gastroenterol. 2005,11(33):5156-61.
3.Hwang HJ,et al. Biol Pharm Bull. 2008,31(8):1559-64.
包装清单：| 产品编号 | 产品名称 | 包装 |
| SM9024-10mM | 苦杏仁苷(98%, HPLC) | 10mM×0.2ml |
| SM9024-25mg | 苦杏仁苷(98%, HPLC) | 25mg |
| SM9024-100mg | 苦杏仁苷(98%, HPLC) | 100mg |
| － | 说明书 | 1份 |
-20℃保存，至少一年有效。固体粉末4℃保存，至少一个月有效。如果溶于非DMSO溶剂，建议分装后-80℃保存，预计6个月内有效。
注意事项：本产品可能对人体有一定的毒害作用，请注意适当防护，以避免直接接触人体或吸入体内。
本产品仅限于专业人员的科学研究用，不得用于临床诊断或治疗，不得用于食品或药品，不得存放于普通住宅内。
为了您的安全和健康，请穿实验服并戴一次性手套操作。
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