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SMT(iNOS抑制剂) |
产品编号: S0008
产品包装: 100mg
产品价格: 165.00元 |
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产品简介
产品简介:
SMT,即S-Methylisothiourea Sulfate,也称2-Methyl-2-thiopseudourea,Sulfate,或
S-Methyl-ITU,是iNOS(inducible nitric oxide synthase)高度选择性抑制剂。对于体外培养巨噬细胞诱导产生的iNOS,EC50=6μM;对于血管平滑肌细胞被诱导产生的iNOS,EC50=2μM。
SMT为白色结晶,分子量278.4,分子式为(C2H6N2S)2·H2SO4,纯度大于99%。
溶解于水;用1M盐酸可以配制成25mg/ml的无色透明溶液。
包装清单:
产品编号 |
产品名称 |
包装 |
S0008 |
SMT(iNOS抑制剂) |
100mg |
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说明书 |
1份 |
保存条件:
室温保存,两年有效。
注意事项:
如果配制成水溶液,分装后-20℃保存,半年有效。
为了您的安全和健康,请穿实验服并戴一次性手套操作。
使用说明
使用说明:
SMT的工作浓度通常为0.1-1mM。其最佳工作浓度需根据具体的实验,自行摸索。可以先分别尝试0.1、
0.3和1mM这三个浓度。
产品图片
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相关论文
使用本产品的文献:
1. Zhang F, Liao L, Ju Y, Song A, Liu Y.
Neurochemical plasticity of nitric oxide synthase isoforms in neurogenic detrusor
overactivityafter spinal cord injury.
Neurochem Res. 2011 Oct;36(10):1903-9.
2. Li W, Ren G, Huang Y, Su J, Han Y, Li J, Chen X, Cao K, Chen Q, Shou P, Zhang L, Yuan
ZR, Roberts AI, Shi S, Le AD, Shi Y.
Mesenchymal stem cells: a double-edged sword in regulating immune responses.
Cell Death Differ. 2012 Mar 16.
3. Xu J, Jin DQ, Zhao P, Song X, Sun Z, Guo Y, Zhang L.
Sesquiterpenes inhibiting NO production from Celastrus orbiculatus.
Fitoterapia. 2012 Jan 8.
4. Mao YF, Zhang YL, Yu QH, Jiang YH, Wang XW, Yao Y, Huang JL.
Chronic restraint stress aggravated arthritic joint swell of rats through regulating
nitric oxide production.
Nitric Oxide. 2012 Oct 15;27(3):137-42. doi: 10.1016/j.niox.2012.06.005.
Epub 2012 Jun 25.
5. Jiang Q, Zhou Z, Wang L, Shi X, Wang J, Yue F, Yi Q, Yang C, Song L.
The immunomodulation of inducible nitric oxide in scallop Chlamys farreri.
Fish Shellfish Immunol. 2013 Jan;34(1):100-8. doi: 10.1016/j.fsi.2012.10.011.
Epub 2012 Oct 13.
6.Yan K, Zhang R, Chen L, Chen F, Liu Y, Peng L, Sun H, Huang W, Sun C, Lv B, Li F, Cai Y,
Tang Y, Zou Y, Du M, Qin L, Zhang H, Jiang X.
Nitric oxide-mediated immunosuppressive effect of human amniotic membrane-derived
mesenchymal stem cells on the viability and migration of microglia.
Brain Res. 2014 Jun 6. pii: S0006-8993(14)00756-2. doi: 10.1016/j.brainres.
2014.05.041.
7. Sun Z, Jiang Q, Wang L, Zhou Z, Wang M, Yi Q, Song L.
The comparative proteomics analysis revealed the modulation of inducible nitric oxide on
the immune response of scallop Chlamys farreri.
Fish Shellfish Immunol. 2014 Oct;40(2):584-94. doi: 10.1016/j.fsi.2014.08.015. Epub
2014 Aug 19.
8. Li Y, Ma C, Shi X, Wen Z, Li D, Sun M, Ding H.
Effect of nitric oxide synthase on multiple drug resistance is related to Wnt signaling
in non-small cell lung cancer.
Oncol Rep. 2014 Oct;32(4):1703-8. doi: 10.3892/or.2014.3351. Epub 2014 Jul 23.
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