Mito-Tracker Green (线粒体绿色荧光探针)(C1048)

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试剂> 细胞相关> 细胞组织染色> 荧光染色

Mito-Tracker Green (线粒体绿色荧光探针)

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产品编号: C1048

产品包装:50μg

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价格: ¥ 327.00

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产品编号	产品名称	产品包装	产品价格
C1048	Mito-Tracker Green (线粒体绿色荧光探针)	50μg	327.00元

Mito-Tracker Green，也称MitoTracker Green，是一种线粒体(mitochondria)绿色荧光探针，可以用于活细胞线粒体特异性荧光染色。
Mito-Tracker Green为采用Molecular Probes公司的carbocyanine进行了荧光标记的一种Mito-Tracker，也称Benzoxazolium, 2-[3-[5,6-dichloro-1,3-bis[[4-(chloromethyl)phenyl]methyl]-1,3-dihydro-2H-benzimidazol-2-ylidene]-1-propenyl]-3-methyl-, chloride。分子式为C₃₄H₂₈Cl₅N₃O，分子量为671.88，CAS number为201860-17-5，可以用作线粒体特异性的荧光探针。和Rhodamine 123或JC-1相比，Mito-Tracker Green对于线粒体的染色不依赖于线粒体膜电位。
Mito-Tracker Green只可以用于对活细胞的染色，细胞经过固定后会导致荧光会消失。Mito-Tracker Green对活细胞的染色效果参考图1。

图1.Mito-Tracker Green(线粒体绿色荧光探针)对于NRK-52E细胞(大鼠肾小管上皮细胞)的染色效果。Mito-Tracker Green染色的NRK-52E细胞其线粒体呈现绿色荧光(图B)，Lyso-Tracker Red (C1046)染色的NRK-52E细胞其溶酶体呈现红色荧光(图C)，绿色荧光、红色荧光及细胞核蓝色荧光的叠加(merge)效果见图D。其中细胞核使用Hoechst 33342 (C1027)染色。本图仅作参考，实际检测效果会因实验条件、检测仪器等的不同而存在差异。
Mito-Tracker Green最大激发光波长为490nm，最大发射波长为516nm，呈绿色荧光，Mito-Tracker Green的结构式以及激发光谱和发射光谱参考图2。

图2.Mito-Tracker Green的结构式(左)以及激发光谱和发射光谱(右)。

按最终工作浓度为20-200nM计算，可以配制约370-3700ml Mito-Tracker Green工作液。
包装清单：

产品编号	产品名称	包装
C1048	Mito-Tracker Green	50μg
－	说明书	1份

保存条件：
-20℃避光保存，半年有效。
注意事项：
Mito-Tracker Green可以用于活细胞的线粒体荧光标记，但不适合用于固定细胞的标记。
对于微量的液体，每次使用前先离心数秒钟，使液体充分沉降到管底。
荧光染料均存在淬灭问题，请尽量注意避光，以减缓荧光淬灭。
需自备盖玻片和载玻片(可以向碧云天订购)。
本产品仅限于专业人员的科学研究用，不得用于临床诊断或治疗，不得用于食品或药品，不得存放于普通住宅内。
为了您的安全和健康，请穿实验服并戴一次性手套操作。

使用说明：
1. Mito-Tracker Green储存液的配制：
用无水DMSO(anhydrous dimethylsulfoxide)配制Mito-Tracker Green至终浓度为1mM。配制后可以-20℃或更低温度避光保存。
2. Mito-Tracker Green工作液的配制：
a. 取少量1mM Mito-Tracker Green储存液按照1:5000-1:50000的比例加入到细胞培养液或适当的溶液(例如含钙镁离子的HBSS)中，使最终浓度为20-200nM。例如取1μl Mito-Tracker Green加入到50ml或5ml细胞培养液或适当的溶液(例如含钙镁离子的HBSS)中。混匀后即为Mito-TrackerGreen工作液。 HBSS with Ca²⁺ & Mg²⁺ (C0219)可以向碧云天订购。
b. Mito-Tracker Green工作液使用前需37℃预温育。
注：工作液中Mito-Tracker Green的浓度可以根据实际情况进行适当调整。为降低背景，在染色效果可以接受的范围内，建议尽量使用较低浓度的Mito-Tracker Green。
3. 线粒体的荧光标记：
a. 去除细胞培养液，加入步骤2配制好的并37℃预温育的Mito-Tracker Green染色工作液，与细胞37℃共孵育15-45分钟。
b. 去除Mito-Tracker Green染色工作液，加入37℃预温育的新鲜细胞培养液。
c. 随后通常用荧光显微镜或激光共聚焦显微镜进行观察。此时可观察到线粒体呈明亮的强荧光染色。如果染色效果欠佳，可以提高Mito-Tracker Green染色工作液中Mito-Tracker Green的浓度或在推荐的时间范围内适当延长染色时间。

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Biomed Res Int. 2017;2017:1314297. (IF 2.276)

63. Dong ZQ, Hu N, Dong FF, Chen TT, Jiang YM, Chen P, Lu C, Pan MH.

Baculovirus LEF-11 Hijack Host ATPase ATAD3A to Promote Virus Multiplication in Bombyx moricells.

SCI REP-UK. 2017 Apr 10;7:46187. (IF 3.998)

64. Chen X, Wang P, Guo F, Wang X, Wang J, Xu J, Yuan D, Zhang J, Shao C.

Autophagy enhanced the radioresistance of non-small cell lung cancer by regulating ROS levelunder hypoxia condition.

Int J Radiat Biol. 2017 Aug;93(8):764-770. (IF 2.368)

65. Geng Y, Zhou Y, Wu S, Hu Y, Lin K, Wang Y, Zheng Z, Wu W.

Sulforaphane Induced Apoptosis via Promotion of Mitochondrial Fusion and ERK1/2-Mediated26S Proteasome Degradation of Novel Pro-survival Bim and Upregulation of Bax in Human Non-Small Cell Lung Cancer Cells.

J Cancer. 2017 Aug 2;8(13):2456-2470. (IF 3.565)

66. Zhang J, Wang Y, Zhou Y, He QY.

Jolkinolide B induces apoptosis of colorectal carcinoma through ROS-ER stress-Ca2+-mitochondria dependent pathway.

ONCOTARGET. 2017 Aug 9;8(53):91223-91237. (IF 5.168)

67. Bin Feng, Meng R, Bin Huang, Bi Y, Shen S, Zhu D.

Silymarin protects against renal injury through normalization of lipid metabolism and mitochondrial biogenesis in high fat-fed mice.

FREE RADICAL BIO MED. 2017 Sep;110:240-249. (IF 6.17)

68. Tong H, Zhang L, Gao J, Wen S, Zhou H, Feng S.

Methylation of mitochondrial DNA displacement loop region regulates mitochondrial copynumber in colorectal cancer.

Mol Med Rep. 2017 Oct;16(4):5347-5353. (IF 2.1)

69. Liu T, Chen XM, Sun JY, Jiang XS, Wu Y, Yang S, Huang HZ, Ruan XZ, Du XG

Palmitic Acid-Induced Podocyte Apoptosis via the Reactive Oxygen Species-Dependent Mitochondrial Pathway.

KIDNEY BLOOD PRESS R. 2018;43(1):206-219. (IF 1.898)

70. Zhang J, Li L, Peng Y, Chen Y, Lv X, Li S, Qin X, Yang H, Wu C, Liu Y.

Surface chemistry induces mitochondria-mediated apoptosis of breast cancer cells viaPTEN/PI3K/AKT signaling pathway.

BBA-BIOMEMBRANES. 2018 Jan;1865(1):172-185. (IF 3.411)

71. Zhang J, Li L, Peng Y, Chen Y, Lv X, Li S, Qin X, Yang H, Wu C, Liu Y

Surface chemistry induces mitochondria-mediated apoptosis of breast cancer cells via PTEN/PI3K/AKT signaling pathway.

BBA-MOL CELL RES. 2018 Jan;1865(1):172-185. (IF 4.105)

72. Wen F, An C, Wu X, Yang Y, Xu J, Liu Y, Wang C, Nie L, Fang H, Yang Z

MiR-34a regulates mitochondrial content and fat ectopic deposition induced by resistin through the AMPK/PPARα pathway in HepG2 cells.

INT J BIOCHEM CELL B. 2018 Jan;94:133-145. (IF 3.673)

73. Tan J, Xie Q, Song S, Miao Y, Zhang Q

Albumin Overload and PINK1/Parkin Signaling-Related Mitophagy in Renal Tubular Epithelial Cells.

MED SCI MONITOR. 2018 Mar 1;24:1258-1267. (IF 1.918)

74. Peng K, Hu J, Xiao J, Dan G, Yang L, Ye F, Zou Z, Cao J, Sai Y

Mitochondrial ATP-sensitive potassium channel regulates mitochondrial dynamics to participate in neurodegeneration of Parkinson's disease.

BBA-MOL BASIS DIS. 2018 Apr;1864(4 Pt A):1086-1103. (IF 4.352)

75. Ma S, Zhan X, Yang M, Lan F, Wu Y, Gu Z

Polyethylene Glycol-Functionalized Magnetic Fe₃O₄/P(MMA-AA) Composite Nanoparticles Enhancing Efficient Capture of Circulating Tumor Cells.

J NANOSCI NANOTECHNO. 2018 Apr 1;18(4):2278-2285. (IF 1.134)

76. Zhang F, Ai W, Hu X, Meng Y, Yuan C, Su H, Wang L, Zhu X, Gao P, Shu G, Jiang Q, Wang S

Phytol stimulates the browning of white adipocytes through the activation of AMP-activated protein kinase (AMPK) α in mice fed high-fat diet.

Food Funct. 2018 Apr 25;9(4):2043-2050. (IF 4.171)

77. Jiang XJ, Cretoiu D, Shen ZJ, Yang XJ

An in vitro investigation of telocytes-educated macrophages: morphology, heterocellular junctions, apoptosis and invasion analysis.

J Transl Med. 2018 Apr 3;16(1):85. (IF 4.124)

78. Guo C, Wang J, Jing L, Ma R, Liu X, Gao L, Cao L, Duan J, Zhou X, Li Y, Sun Z

Mitochondrial dysfunction, perturbations of mitochondrial dynamics and biogenesis involved in endothelial injury induced by silica nanoparticles.

Environ Pollut. 2018 May;236:926-936. (IF 6.792)

79. Yang F, Liao J, Pei R, Yu W, Han Q, Li Y, Guo J, Hu L, Pan J, Tang Z

Autophagy attenuates copper-induced mitochondrial dysfunction by regulating oxidative stress in chicken hepatocytes.

Chemosphere. 2018 Aug;204:36-43. (IF 5.778)

80. Xu HY, Yang XG, Lu SS, Liang XW, Lu YQ, Zhang M, Lu KH

Treatment with acetyl-l-carnitine during in vitro maturation of buffalo oocytes improves oocyte quality and subsequent embryonic development.

Theriogenology. 2018 Sep 15;118:80-89. (IF 2.094)

81. Gong X, Sun R, Gao Z, Han W, Liu Y, Zhao L, Jing L, Yao X, Sun X

Tubeimoside 1 Acts as a Chemotherapeutic Synergist via Stimulating Macropinocytosis.

Front Pharmacol. 2018 Sep 26;9:1044. (IF 4.225)

82. Liu JX, Shen SN, Tong Q, Wang YT, Lin LG

Honokiol protects hepatocytes from oxidative injury through mitochondrial deacetylase SIRT3.

Eur J Pharmacol. 2018 Sep 5;834:176-187. (IF 3.263)

83. Li Y, Ma G, Zhao P, Fu R, Gao L, Jiang X, Hu P, Ren T, Wu Y, Wang Z, Cui Z, Yang D

Improvement of sensitive and specific detection of circulating tumor cells using negative enrichment and immunostaining-FISH.

Clin Chim Acta. 2018 Oct;485:95-102. (IF 2.615)

84. Sun K, Gao Z, Zhang Y, Wu H, You C, Wang S, An P, Sun C, Sun B

Enhanced highly toxic reactive oxygen species levels from iron oxide core-shell mesoporous silica nanocarrier-mediated Fenton reactions for cancer therapy.

J Mater Chem B. 2018 Oct 7 6(37):5876-5887. (IF 5.344)

85. Guo C, Ma R, Liu X, Xia Y, Niu P, Ma J, Zhou X, Li Y, Sun Z

Silica nanoparticles induced endothelial apoptosis via endoplasmic reticulum stress-mitochondrial apoptotic signaling pathway.

Chemosphere. 2018 Nov;210:183-192. (IF 5.778)

86. Xie X, Wang J, Yan Y, Zhang X, Liu C, Yang J, Hua J

A new mitochondria-targeted ratiometric fluorescent probe based on diketopyrrolopyrrole for imaging endogenous HOCl in living cells.

Analyst. 2018 Nov 19;143(23):5736-5743. (IF 3.978)

87. Liu B, Jin J, Zhang Z, Zuo L, Jiang M, Xie C

Shikonin exerts antitumor activity by causing mitochondrial dysfunction in hepatocellular carcinoma through PKM2-AMPK-PGC1α signaling pathway.

Biochem Cell Biol. 2018 Nov 26. (IF 2.46)

88. Liu SY, Song JY, Fan B, Wang Y, Pan YR, Che L, Sun YJ, Li GY

Resveratrol protects photoreceptors by blocking caspase- and PARP-dependent cell death pathways.

FREE RADICAL BIO MED. 2018 Dec;129:569-581. (IF 6.17)

89. Hasnat M, Yuan Z, Naveed M, Khan A, Raza F, Xu D, Ullah A, Sun L, Zhang L, Jiang Z

Drp1-associated mitochondrial dysfunction and mitochondrial autophagy: a novel mechanism in triptolide-induced hepatotoxicity.

Cell Biol Toxicol. 2018 Dec 13. (IF 6.284)

90. Wu H, You C, Jiao J, Chen F, Sun B, Zhu X

A novel near-infrared triggered dual-targeted nanoplatform for mitochondrial combined photothermal-chemotherapy of cancer in vitro.

Nanotechnology. 2019 Jan 18;30(3):035601. (IF 3.551)

91. Li Z, Li Q, Lv W, Jiang L, Geng C, Yao X, Shi X, Liu Y, Cao J

The interaction of Atg4B and Bcl-2 plays an important role in Cd-induced crosstalk between apoptosis and autophagy through disassociation of Bcl-2-Beclin1 in A549 cells.

FREE RADICAL BIO MED. 2019 Jan 130:576-591. (IF 6.17)

92. Yao X, Zhang J, Jing X, Ye Y, Guo J, Sun K, Guo F

Fibroblast growth factor 18 exerts anti-osteoarthritic effects through PI3K-AKT signaling and mitochondrial fusion and fission.

Pharmacol Res. 2019 Jan 139:314-324. (IF 5.893)

93. Mai CT, Wu MM, Wang CL, Su ZR, Cheng YY, Zhang XJ

Palmatine attenuated dextran sulfate sodium (DSS)-induced colitis via promoting mitophagy-mediated NLRP3 inflammasome inactivation.

Mol Immunol. 2019 Jan 105:76-85. (IF 3.641)

94. Lei P, Tian S, Teng C, Huang L, Liu X, Wang J, Zhang Y, Li B, Shan Y

Sulforaphane Improves Lipid Metabolism by Enhancing Mitochondrial Function and Biogenesis In Vivo and In Vitro.

Mol Nutr Food Res. 2019 Feb;63(4):e1800795. (IF 5.309)

95. Peng K, Xiao J, Yang L, Ye F, Cao J, Sai Y

Mutual Antagonism of PINK1/Parkin and PGC-1α Contributes to Maintenance of Mitochondrial Homeostasis in Rotenone-Induced Neurotoxicity.

Neurotox Res. 2019 Feb 35(2):331-343. (IF 2.992)

96. Cai J, Yang J, Liu Q, Gong Y, Zhang Y, Zhang Z

Selenium deficiency inhibits myocardial development and differentiation by targeting the mir-215-5p/CTCF axis in chicken.

Metallomics. 2019 Feb 20 11(2):415-428. (IF 3.796)

97. Yao X, Jing X, Guo J, Sun K, Deng Y, Zhang Y, Guo F, Ye Y

Icariin Protects Bone Marrow Mesenchymal Stem Cells Against Iron Overload Induced Dysfunction Through Mitochondrial Fusion and Fission, PI3K/AKT/mTOR and MAPK Pathways.

Front Pharmacol. 2019 Feb 28 10:163. (IF 4.225)

98. Zhang C, Ma C, Zhang L, Zhang L, Zhang F, Ma M, Zheng X, Mao M, Shen T, Zhu D

MiR-449a-5p mediates mitochondrial dysfunction and phenotypic transition by targeting Myc in pulmonary arterial smooth muscle cells.

J MOL MED. 2019 Mar 97(3):409-422. (IF 4.427)

99. Huang L, Chen Q, Yu L, Bai D

Pyropheophorbide-α methyl ester-mediated photodynamic therapy induces apoptosis and inhibits LPS-induced inflammation in RAW264.7 macrophages.

PHOTODIAGN PHOTODYN. 2019 Mar 25:148-156. (IF 2.894)

100. Xu D, Wu L, Jiang X, Yang L, Cheng J, Chen H, Hua R, Geng G, Yang L, Li Q

SIRT2 Inhibition Results in Meiotic Arrest, Mitochondrial Dysfunction, and Disturbance of Redox Homeostasis during Bovine Oocyte Maturation.

Int J Mol Sci. 2019 Mar 18 20(6). pii: E1365. (IF 4.556)

101. Zhang LS, Shen SN, Gao YL, Shi SY, Zhou CX, Mo JX, Xu YK, Lin LG, Gan LS

Tautomerism and bioactivities of curcumenol, a common sesquiterpenoid widely existing in edible plants.

Food Funct. 2019 Mar 20 10(3):1288-1294. (IF 4.171)

102. Lu Z, Zhang C, Han C, An Q, Cheng Y, Chen Y, Meng R, Zhang Y, Su J

Plasticizer Bis(2-ethylhexyl) Phthalate Causes Meiosis Defects and Decreases Fertilization Ability of Mouse Oocytes in Vivo.

J AGR FOOD CHEM. 2019 Mar 27 67(12):3459-3468. (IF 4.192)

103. Zhong Y, Zeng L, Deng J, Duan Y, Li F

β-hydroxy-β-methylbutyrate (HMB) improves mitochondrial function in myocytes through pathways involving PPARβ/δ and CDK4.

Nutrition. 2019 Apr 60:217-226. (IF 3.639)

104. Liu M, Zheng M, Cai D, Xie J, Jin Z, Liu H, Liu J

Zeaxanthin promotes mitochondrial biogenesis and adipocyte browning via AMPKα1 activation.

Food Funct. 2019 Apr 17 10(4):2221-2233. (IF 4.171)

105. Zhou C, Zhao WX, You FT, Geng ZX, Peng HS

Highly Stable and Luminescent Oxygen Nanosensor Based on Ruthenium-Containing Metallopolymer for Real-Time Imaging of Intracellular Oxygenation.

ACS Sens. 2019 Apr 26 4(4):984-991.

106. Qi R, Wang J, Wang Q, Qiu X, Yang F, Liu Z, Huang J

MicroRNA-425 controls lipogenesis and lipolysis in adipocytes.

BBA-MOL CELL BIOL L. 2019 May 1864(5):744-755. (IF 4.519)

107. Sun L, Chen Y, Luo H, Xu M, Meng G, Zhang W

Ca2+/calmodulin-dependent protein kinase II regulation by inhibitor 1 of protein phosphatase 1 alleviates necroptosis in high glucose-induced cardiomyocytes injury.

Biochem Pharmacol. 2019 May 163:194-205. (IF 4.96)

108. Yu X, Hu L, He H, Zhang F, Wang M, Wei W, Xia Z

Y-shaped DNA-Mediated hybrid nanoflowers as efficient gene carriers for fluorescence imaging of tumor-related mRNA in living cells.

Anal Chim Acta. 2019 May 30 1057:114-122. (IF 5.977)

109. Sun Y, Niu Y, Huang H, He B, Ma L, Tu Y, Tran VT, Zeng B, Hu Z.

Mevalonate Diphosphate Decarboxylase MVD/Erg19 Is Required for Ergosterol Biosynthesis, Growth, Sporulation and Stress Tolerance in Aspergillus oryzae.

Front Microbiol. 2019 May 16 10:1074. (IF 4.235)

110. Zhang L, Ma C, Wang X, He S, Li Q, Zhou Y, Liu Y, Zhang M, Yu X, Zhao X, Li F, Zhu DL

Lipopolysaccharide-induced proliferation and glycolysis in airway smooth muscle cells via activation of Drp1.

J Cell Physiol. 2019 Jun;234(6):9255-9263. (IF 5.546)

111. Chen Y, Xiong S, Zhao F, Lu X, Wu B, Yang B

Effect of magnesium on reducing the UV-induced oxidative damage in marrow mesenchymal stem cells.

J Biomed Mater Res A. 2019 Jun 107(6):1253-1263. (IF 3.525)

112. Chu Q, Zhang S, Yu L, Li Y, Liu Y, Ye X, Zheng X

Apios americana Medikus tuber polysaccharide exerts anti-inflammatory effects by activating autophagy.

Int J Biol Macromol. 2019 Jun 1 130:892-902. (IF 5.162)

113. Guo T, Liu T, Sun Y, Liu X, Xiong R, Li H, Li Z, Zhang Z, Tian Z, Tian Y

Sonodynamic therapy inhibits palmitate-induced beta cell dysfunction via PINK1/Parkin-dependent mitophagy.

Cell Death Dis. 2019 Jun 11 10(6):457. (IF 6.304)

114. Xu C, Qiao L, Ma L, Guo Y, Dou X, Yan S, Zhang B, Roman A

Biogenic selenium nanoparticles synthesized by Lactobacillus casei ATCC 393 alleviate intestinal epithelial barrier dysfunction caused by oxidative stress via Nrf2 signaling-mediated mitochondrial pat

INT J NANOMED. 2019 Jun 18 14:4491-4502. (IF 5.115)

115. Yu J, Zheng J, Lu J, Sun Z, Wang Z, Zhang J

AdipoRon Protects Against Secondary Brain Injury After Intracerebral Hemorrhage via Alleviating Mitochondrial Dysfunction: Possible Involvement of AdipoR1-AMPK-PGC1α Pathway.

Neurochem Res. 2019 Jul 44(7):1678-1689. (IF 3.038)

116. Yuan Y, Chen Y, Peng T, Li L, Zhu W, Liu F, Liu S, An X, Luo R, Cheng J, Liu J, Lu Y

Mitochondrial ROS-induced lysosomal dysfunction impairs autophagic flux and contributes to M1 macrophage polarization in a diabetic condition.

CLIN SCI. 2019 Aug 14 133(15):1759-1777. (IF 5.223)

117. Shan C, Gong YL, Zhuang QQ, Hou YF, Wang SM, Zhu Q, Huang GR, Tao B, Sun LH, Zhao HY, Li ST, Liu JM

Protective effects of β- nicotinamide adenine dinucleotide against motor deficits and dopaminergic neuronal damage in a mouse model of Parkinson's disease.

PROG NEURO-PSYCHOPH. 2019 Aug 30 94:109670. (IF 4.361)

118. Chen J, Li D, Huo B, Zhang F, Zhao X, Yuan G, Chen D, Song M, Xue J

Epidermal Growth Factor Receptor-Targeted Delivery of a Singlet-Oxygen Sensitizer with Thermal Controlled Release for Efficient Anticancer Therapy.

MOL PHARMACOL. 2019 Aug 5 16(8):3703-3710. (IF 3.664)

119. Xu D, Jiang X, He H, Liu D, Yang L, Chen H, Wu L, Geng G, Li Q

SIRT2 functions in aging, autophagy, and apoptosis in post-maturation bovine oocytes.

Life Sci. 2019 Sep 1 232:116639. (IF 3.647)

120. Cheng Y, Zhang J, Wu T, Jiang X, Jia H, Qing S, An Q, Zhang Y, Su J

Reproductive toxicity of acute Cd exposure in mouse: Resulting in oocyte defects and decreased female fertility.

TOXICOL APPL PHARM . 2019 Sep 15 379:114684. (IF 3.616)

121. Hu Q, Zhao F, Fan M, He C, Yang X, Huang Z, Fu Z.

The influence of titanium dioxide nanoparticles on their cellular response to macrophage cells.

COMP BIOCHEM PHYS C. 2019 Sep 223:42-52. (IF 2.892)

122. Jingjing An, Yu Zhou, Mengjun Zhang, Yunzhen Xie, Sujie Ke, Libin Liu, Xiaodong Pan, Zhou Chen

Exenatide Alleviates Mitochondrial Dysfunction and Cognitive Impairment in the 5×FAD Mouse Model of Alzheimer's Disease

Behav Brain Res. 2019 Sep 16;370:111932. doi: 10.1016/j.bbr.2019.111932. (IF 2.977)

123. Liu H, Liu Z, Lu T, Zhang L, Cheng J, Fu X, Hou Y

Toxic effects of 1-(N-methyl-N-nitrosamino)-1-(3-pyridinyl)-4-butanal on the maturation and subsequent development of murine oocyte.

ECOTOX ENVIRON SAFE. 2019 Oct 15 181:370-380. (IF 4.872)

124. Ren KD, Liu WN, Tian J, Zhang YY, Peng JJ, Zhang D, Li NS, Yang J, Peng J, Luo XJ

Mitochondrial E3 ubiquitin ligase 1 promotes brain injury by disturbing mitochondrial dynamics in a rat model of ischemic stroke.

Eur J Pharmacol. 2019 Oct 15 861:172617. (IF 3.263)

125. Guan L, Che Z, Meng X, Yu Y, Li M, Yu Z, Shi H, Yang D, Yu M

MCU Up-regulation contributes to myocardial ischemia-reperfusion Injury through calpain/OPA-1-mediated mitochondrial fusion/mitophagy Inhibition.

J Cell Mol Med. 2019 Nov 23(11):7830-7843. (IF 4.486)

126. Liu Y, Zhong Y, Tian W, Lan F, Kang J, Pang H, Hou H, Li D

An autophagy-dependent cell death of MDA-MB-231 cells triggered by a novel Rhein derivative 4F.

ANTI-CANCER DRUG. 2019 Nov 30(10):1038-1047. (IF 2.26)

127. Zhao M, Gao Y, Ye S, Ding J, Wang A, Li P, Shi H

A light-up near-infrared probe with aggregation-induced emission characteristics for highly sensitive detection of alkaline phosphatase.

Analyst. 2019 Nov 7 144(21):6262-6269. (IF 3.978)

128. Tianshu Wu, Xue Liang, Keyu He, Tingting Wei, Yan Wang, Lingyue Zou, Changcun Bai, Na Liu, Ting Zhang, Yuying Xue, Meng Tang

The Role of NLRP3 Inflammasome Activation in the Neuroinflammatory Responses to Ag 2 Se Quantum Dots in Microglia

Nanoscale. 2019 Nov 21;11(43):20820-20836. doi: 10.1039/c9nr06778g. (IF 6.895)

129. Ren L, Han F, Xuan L, Lv Y, Gong L, Yan Y, Wan Z, Guo L, Liu H, Xu B, Sun Y, Yang S, Liu L

Clusterin ameliorates endothelial dysfunction in diabetes by suppressing mitochondrial fragmentation.

FREE RADICAL BIO MED. 2019 Dec 145:357-373. (IF 6.17)

130. Chen P, Zhong J, Ye J, He Y, Liang Z, Cheng Y, Zheng J, Chen H, Chen C

miR-324-5p protects against oxidative stress-induced endothelial progenitor cell injury by targeting Mtfr1.

J Cell Physiol. 2019 Dec 234(12):22082-22092. (IF 5.546)

131. Fan JH, Fan GL, Yuan P, Deng FA, Liu LS, Zhou X, Yu XY, Cheng H, Li SY.

A Theranostic Nanoprobe for Hypoxia Imaging and Photodynamic Tumor Therapy.

Front Chem. 2019 Dec 20 7:868. (IF 3.693)

132. Dong C, Tu W, He M, Fu J, Kobayashi A, Konishi T, Shao C

Role of Endoplasmic Reticulum and Mitochondrion in Proton Microbeam Radiation-Induced Bystander Effect.

Radiat Res. 2020 Jan 193(1):63-72. (IF 2.657)

133. Xiaoyan Wang, Zhufeng Chen, Xuemei Fan, Wei Li, Jiaqi Qu, Chuan Dong, Zhixue Wang, Zhenwei Ji, Yang Li

Inhibition of DNM1L and mitochondrial fission attenuates inflammatory response in fibroblast-like synoviocytes of rheumatoid arthritis

J Cell Mol Med. 2020 Jan;24(2):1516-1528. doi: 10.1111/jcmm.14837. (IF 4.486)

134. Wei Xue, Xin Wang, Hong Tang, Fanfan Sun, Huaqing Zhu, Dake Huang, Liuyi Dong

Vitexin attenuates myocardial ischemia/reperfusion injury in rats by regulating mitochondrial dysfunction induced by mitochondrial dynamics imbalance

Biomed Pharmacother. 2020 Apr;124:109849. doi: 10.1016/j.biopha.2020.109849. (IF 4.545)

135. Shengju Yang, Mengting Xu, Guoliang Meng, Yan Lu

SIRT3 deficiency delays diabetic skin wound healing via oxidative stress and necroptosis enhancement

J Cell Mol Med. 2020 Apr;24(8):4415-4427. doi: 10.1111/jcmm.15100. (IF 4.486)

136. Jia H, Jia C, An Q, Cheng Y, Jiang X, Xu Y, Zhao R, Peng W, Zhang Y, Su J

Ochratoxin A exposure causes meiotic failure and oocyte deterioration in mice.

Theriogenology. 2020 May 148:236-248. (IF 2.094)

137. Xu-Shun Jiang, Xue-Mei Chen, Wei Hua, Jun-Ling He, Ting Liu, Xun-Jia Li, Jiang-Min Wan, Hua Gan, Xiao-Gang Du

PINK1/Parkin mediated mitophagy ameliorates palmitic acid-induced apoptosis through reducing mitochondrial ROS production in podocytes

BIOCHEM BIOPH RES CO. 2020 May 14;525(4):954-961. doi: 10.1016/j.bbrc.2020.02.170. (IF 2.985)

138. Xilu Hu, Ting Huang, Hong Liao, Lianzhe Hu, Min Wang

The phosphatase-like activity of zirconium oxide nanoparticles and their application in near-infrared intracellular imaging

J Mater Chem B. 2020 May 27;8(20):4428-4433. doi: 10.1039/d0tb00450b. (IF 5.344)

139. Jue Tu, Liqun Deng, Yun Ling, Keyan Zhu, Yueqin Cai, Dejun Wang, Zhaowei Cai

Transcriptome profiling reveals multiple pathways responsible for the beneficial metabolic effects of Smilax glabra flavonoids in mouse 3T3-L1 adipocytes

Biomed Pharmacother. 2020 May;125:110011. doi: 10.1016/j.biopha.2020.110011. (IF 4.545)

140. Yujia Yuan, Lan Li, Lingling Zhu, Fei Liu, Xi Tang, Guangneng Liao, Jingping Liu, Jingqiu Cheng, Younan Chen, Yanrong Lu

Mesenchymal stem cells elicit macrophages into M2 phenotype via improving transcription factor EB-mediated autophagy to alleviate diabetic nephropathy

Stem Cells. 2020 May;38(5):639-652. doi: 10.1002/stem.3144. (IF 6.022)

141. Na Chen, Xiaofeng Tang, Zhaoyang Ye, Shanshan Wang, Xianjin Xiao

Methylmercury disrupts autophagic flux by inhibiting autophagosome-lysosome fusion in mouse germ cells

ECOTOX ENVIRON SAFE. 2020 Jul 15;198:110667. doi: 10.1016/j.ecoenv.2020.110667. (IF 4.872)

142. Yujing Zhang, Huanfeng Bian, Yu Ma, Yuanyuan Xiao, Fang Xiao

Cr(VI)-induced overactive mitophagy contributes to mitochondrial loss and cytotoxicity in L02 hepatocytes

Biochem J. 2020 Jul 31;477(14):2607-2619. doi: 10.1042/BCJ20200262. (IF 4.097)

143. Xing-Hua Wang, Shen Yin, Xiang-Hong Ou, Shi-Ming Luo

Increase of mitochondria surrounding spindle causes mouse oocytes arrested at metaphase I stage

BIOCHEM BIOPH RES CO. 2020 Jul 5;527(4):1043-1049. doi: 10.1016/j.bbrc.2020.05.037. (IF 2.985)

144. Xuan Wang, Zhiguo Li, Zeyun Gao, Qiujuan Li, Liping Jiang, Chengyan Geng, Xiaofeng Yao, Xiaoxia Shi, Yong Liu, Jun Cao

Cadmium induces cell growth in A549 and HELF cells via autophagy-dependent glycolysis

Toxicol In Vitro. 2020 Aug;66:104834. doi: 10.1016/j.tiv.2020.104834. (IF 2.959)

145. Dandan Luo, Meijie Zhang, Xiaohui Su, Luna Liu, Xinli Zhou, Xiujuan Zhang, Dongmei Zheng, Chunxiao Yu, Qingbo Guan

High fat diet impairs spermatogenesis by regulating glucose and lipid metabolism in Sertoli cells

Life Sci. 2020 Sep 15;257:118028. doi: 10.1016/j.lfs.2020.118028. (IF 3.647)

146. Ranyue Ren, Jiachao Guo, Jia Shi, Yong Tian, Mengwei Li, Hao Kang

PKM2 regulates angiogenesis of VR-EPCs through modulating glycolysis, mitochondrial fission, and fusion

J Cell Physiol. 2020 Sep;235(9):6204-6217. doi: 10.1002/jcp.29549. (IF 5.546)

147. Xiuge Gao, Xiangchun Ruan, Hui Ji, Lin Peng, Yawei Qiu, Dan Yang, Xinhao Song, Chunlei Ji, Dawei Guo, Shanxiang Jiang

Maduramicin triggers methuosis-like cell death in primary chicken myocardial cells

Toxicol Lett. 2020 Oct 15;333:105-114. doi: 10.1016/j.toxlet.2020.07.025. (IF 3.569)

148. Yun Yang, Yang Zhang, Jufang Gao, Wenping Xu, Zhiping Xu, Zhong Li, Jiagao Cheng, Liming Tao

Pyrethrum extract induces oxidative DNA damage and AMPK/mTOR-mediated autophagy in SH-SY5Y cells

Sci Total Environ. 2020 Oct 20;740:139925. doi: 10.1016/j.scitotenv.2020.139925. (IF 6.551)

149. Xiao-Ying Zhu, Wen Liu, Hai-Tao Liang, Ling Tang, Ping Zou, Yong You, Xiao-Jian Zhu

AICAR and Decitabine Enhance the Sensitivity of K562 Cells to Imatinib by Promoting Mitochondrial Activity

Curr Med Sci. 2020 Oct;40(5):871-878. doi: 10.1007/s11596-020-2266-1. (IF 1.273)

150. Shichen Xu, Xian Cheng, Liying Wu, Jiangxia Zheng, Xiaowen Wang, Jing Wu, Huixin Yu, Jiandong Bao, Li Zhang

Capsaicin induces mitochondrial dysfunction and apoptosis in anaplastic thyroid carcinoma cells via TRPV1-mediated mitochondrial calcium overload

Cell Signal. 2020 Nov;75:109733. doi: 10.1016/j.cellsig.2020.109733. (IF 3.968)

151. Qian Chai, Jiajing Miao, Meili Liu, Ziying Zhang, Ziang Meng, Weihua Wu

SGLT1 knockdown prevents glucose fluctuation-induced apoptosis of cardiomyocytes through attenuating oxidative stress and mitochondrial dysfunction

Biochem Cell Biol. 2020 Dec 1. doi: 10.1139/bcb-2020-0491. (IF 2.46)

152. Shiyuan Huang, Xiaona Wang, Jiale Yu, Yu Tian, Chenkai Yang, Yang Chen, Hua Chen, Hongshan Ge

LonP1 regulates mitochondrial network remodeling through the PINK1/Parkin pathway during myoblast differentiation

AM J PHYSIOL-CELL PH. 2020 Dec 1;319(6):C1020-C1028. doi: 10.1152/ajpcell.00589.2019. (IF 3.485)

153. Xiaoyu Zhang, Tianyu Zhai, Zhenyu Hei, Di Zhou, Longyang Jin, Chao Han, Jiandong Wang

Effects of Platycodin D on apoptosis, migration, invasion and cell cycle arrest of gallbladder cancer cells

Oncol Lett. 2020 Dec;20(6):311. doi: 10.3892/ol.2020.12174. (IF 2.311)

154. Xingzhi Jing, Ting Du, Xiaoxia Yang, Weimin Zhang, Guodong Wang, Xiaoyang Liu, Tao Li, Zhensong Jiang

Desferoxamine protects against glucocorticoid-induced osteonecrosis of the femoral head via activating HIF-1α expression

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155. Zhongyuan Piao, Lin Song, Lifen Yao, Limei Zhang, Yichan Lu

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156. Nanshan Song, Hong Zhu, Rong Xu, Jiaqi Liu, Yinquan Fang, Jing Zhang, Jianhua Ding, Gang Hu, Ming Lu

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159. Xupeng Xing, Jinjing Zhang, Teng Wu, Jingcheng Zhang, Yongsheng Wang, Jianmin Su, Yong Zhang

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160. Fengyun Wen, Zhuoyan Shi, Xiaoping Liu, Yuguang Tan, Lan Wei, Xuemin Zhu, Hui Zhang, Xiaohuan Zhu, Xiangmiao Meng, Weixia Ji, Mengting Yang, Zhaoxuan Lu

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162. Zhonghai Shen, Kang Ji, Zhenhai Cai, Chenglong Huang, Xiaojun He, Hongwei Xu, Gang Chen

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165. Jinling Zhu, Kunyang Liu, Ligang Pei, Xinyue Hu, Yuchen Cai, Jie Ding, Dongmei Li, Xiaodong Han, Jiang Wu

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167. Yan Wang, Jianji Gao, Fan Wu, Caiyun Lai, Yueqi Li, Gaoqiang Zhang, Xinyue Peng, Susu Yu, Jiani Yang, Wei Wang, Wenjuan Zhang, Xingfen Yang

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168. Lizhuo Wang, Cui Yu, Wenjun Pei, Mengya Geng, Yao Zhang, Zihui Li, Feiteng Liang, Fengbiao Tan, Hui Du, Jialin Gao

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169. Cheng Zeng, Tingting Zou, Junyan Qu, Xu Chen, Suping Zhang, Zhenghong Lin

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172. Peng Cui, Ping Zhang, Lin Yuan, Li Wang, Xin Guo, Guanghui Cui, Yanmin Zhang, Minghua Li, Xiaowei Zhang, Xiaoqiang Li, Yuxin Yin, Zhendong Yu

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173. Yinghua Lv, Tianjiao Li, Manman Yang, Lihong Su, Zhendong Zhu, Sihang Zhao, Wenxian Zeng, Yi Zheng

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174. Shuang Gao, Keke Guo, Yu Chen, Jungang Zhao, Rongrong Jing, Lusheng Wang, Xuenan Li, Zhenlin Hu, Nuo Xu, Xiaokun Li

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175. Ying Li, Xiao-Jing Yu, Tong Xiao, Hong-Li Chi, Guo-Qing Zhu, Yu-Ming Kang

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177. Xiangyu Hu, Xiaoqin Jia, Cong Xu, Yingying Wei, Zhengbing Wang, George Liu, Qiang You, Guotao Lu, Weijuan Gong

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178. Haiyan Sun, Tong Ou, Jianyang Hu, Ziyi Yang, Qifang Lei, Yuqing Li, Gang Wang, Yongpeng Li, Kai Wu, Shupeng Wang, Song Wu

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179. Yu Qiu, Ying Yu, Xiao-Mei Qin, Tao Jiang, Yan-Fang Tan, Wen-Xian Ouyang, Zheng-Hui Xiao, Shuang-Jie Li

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180. Su Bu, Chunying Yuan, Fuliang Cao, Qifeng Xu, Yichun Zhang, Ronghua Ju, Longyun Chen, Zhong Li

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182. Hasenbilige, Junjie Mei, Mongameli B Dlamini, Zeyun Gao, Liping Jiang, Qiujuan Li, Chengyan Geng, Xiaoxia Shi, Yong Liu, Ying Kong, Jun Cao

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183. Xingzhi Jing, Qiang Wang, Ting Du, Weimin Zhang, Xiaoyang Liu, Qiang Liu, Tao Li, Guodong Wang, Feifei Chen, Xingang Cui

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187. Lu Yao Zhang, Meng Lin, Zhuan Qingrui, Wang Zichuan, Li Junjin, Liu Kexiong, Fu Xiangwei, Hou Yunpeng

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190. Yakun Wang, Xuan Wang, Qiaoming Long, Yuanwu Liu, Tao Yin, Inna Sirota, Fazheng Ren, Zhenglong Gu, Junjie Luo

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191. Yuejia Dang, Yi Wei, Wajjiha Batool, Xicen Sun, Xiaoqian Li, Shi-Hong Zhang

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192. Delong Jiao, Jing Wang, Wenting Yu, Ke Zhang, Ning Zhang, Lingyan Cao, Xinquan Jiang, Yuxing Bai

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