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| 产品编号 | 产品名称 | 产品包装 | 产品价格 |
| SM8024-10mM | 对羟基苯甲醇(98%, HPLC) | 10mM×0.2ml | 68.00元 |
| SM8024-25mg | 对羟基苯甲醇(98%, HPLC) | 25mg | 52.00元 |
| SM8024-100mg | 对羟基苯甲醇(98%, HPLC) | 100mg | 125.00元 |
| 中文名 | 对羟基苯甲醇 |
| 英文名 | 4-Hydroxybenzyl alcohol |
| 中文别名 | 4-羟基苯甲醇 |
| 英文别名 | - |
| 来源 | 天麻Gastrodia elata Bl.；合欢Albizia julibrissin Durazz. |
| 化合物类型 | 酚类(Phenols) |
| 化学式 | C7H8O2 |
| 分子量 | 124.14 |
| CAS号 | 623-05-2 |
| 纯度 | 98%, HPLC |
| 溶剂/溶解度 | DMSO: 100 mg/ml (805.54 mM) |
| 溶液配制 | 2mg加入1.61ml DMSO，或者每1.24mg加入1ml DMSO，配制成10mM溶液。 |
| 产品描述 | 4-Hydroxybenzyl alcohol is a phenolic compound widely distributed in various kinds of plants with anti-inflammatory, anti-oxidant, anti-nociceptive, neuroprotective effects. 4-Hydroxybenzyl alcohol is inhibitor of tumor angiogenesis and growth. | ||||
| 信号通路 | Apoptosis | ||||
| 靶点 | - | - | - | - | - |
| IC50 | - | - | - | - | - |
| 体外研究 | 4-Hydroxybenzyl alcohol inhibits proliferation of eEND2 cells and suppresses the migration of eEND2 cells, accompanied by inhibition of actin filament reorganization. 4-Hydroxybenzyl alcohol induces apoptotic death of tumor cells. | ||||
| 体内研究 | 4-Hydroxybenzyl alcohol possesses antiangiogenic, anti-inflammatory and anti-nociceptive activity possibly via its down-regulating activity on NO production. 4-Hydroxybenzyl alcohol (200 mg/kg) efficiently inhibits growth and angiogenesis of developing tumors. 4-Hydroxybenzyl alcohol ameliorates ischemic injury induced by transient focal cerebral ischemia in rats, and this neuroprotective effect may be partly related to attenuate apoptosis pathway. | ||||
| 临床实验 | N/A | ||||
1.Lim EJ, et al. J Pharm Pharmacol. 2007,59(9):1235-40.
2.Laschke MW, et al. Br J Pharmacol. 2011,163(4):835-44.
3.Laschke MW, et al. Life Sci. 2013,93(1):44-50.
4.Yu SS, et al. Brain Res. 2010,1308:167-75.
包装清单：| 产品编号 | 产品名称 | 包装 |
| SM8024-10mM | 对羟基苯甲醇(98%, HPLC) | 10mM×0.2ml |
| SM8024-25mg | 对羟基苯甲醇(98%, HPLC) | 25mg |
| SM8024-100mg | 对羟基苯甲醇(98%, HPLC) | 100mg |
| － | 说明书 | 1份 |
-20℃保存，至少一年有效。固体粉末4℃保存，至少一个月有效。如果溶于非DMSO溶剂，建议分装后-80℃保存，预计6个月内有效。
注意事项：本产品可能对人体有一定的毒害作用，请注意适当防护，以避免直接接触人体或吸入体内。
本产品仅限于专业人员的科学研究用，不得用于临床诊断或治疗，不得用于食品或药品，不得存放于普通住宅内。
为了您的安全和健康，请穿实验服并戴一次性手套操作。
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