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JC-1
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产品编号: C2005
产品包装: 1mg
产品价格: 768.00元 |
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产品简介
产品简介:
产品编号 |
产品名称 |
产品包装 |
产品价格 |
C2005 |
JC-1 |
1mg |
768.00元 |
JC-1也称CBIC2(3)或5,5′,6,6′-Tetrachloro-1,1′,3,3′-tetraethyl-imidacarbocyanine
iodide,分子式为 C25H27Cl4IN4,分子量为652.23,CAS Number 3520-43-2,纯度>95%。
JC-1是一种广泛用于检测线粒体膜电位(mitochondrial membrane potential)△Ψm 的理想荧光探针。
可以检测细胞、组织或纯化的线粒体膜电位。在线粒体膜电位较高时,JC-1聚集在线粒体的基质(matrix)中,形成聚合物(J-aggregates),可以产生红色荧光;在线粒体膜电位较低时,JC-1不能聚集在线粒体的基质中,此时JC-1为单体(monomer),可以产生绿色荧光。这样就可以非常方便地通过荧光颜色的转变来检测线粒体膜电位的变化。常用红绿荧光的相对比例来衡量线粒体去极化的比例。
线粒体膜电位的下降是细胞凋亡早期的一个标志性事件。通过JC-1从红色荧光到绿色荧光的转变可以很容易地检测到细胞膜电位的下降,同时也可以用JC-1从红色荧光到绿色荧光的转变作为细胞凋亡早期的一个检测指标。
JC-1单体的最大激发波长为514nm,最大发射波长为529nm;JC-1聚合物(J-aggregates)的最大激发波长为585nm,最大发射波长为590nm。实际观察时,使用常规的观察红色荧光和绿色荧光的设置即可。
JC-1稀释和使用时有一些特殊的要求,因此对于初次使用JC-1的用户或对于JC-1的使用不是非常熟悉的用户,我们建议使用碧云天的线粒体膜电位检测试剂盒(JC-1)(C2006),该试剂盒配套提供了一些相关试剂,使用起来更加便捷。
本JC-1溶解在DMSO中,浓度为5mg/ml,共200μl。
包装清单:
产品编号 |
产品名称 |
包装 |
C2005 |
JC-1(5mg/ml) |
50μl/管,共4管 |
— |
说明书 |
1份 |
保存条件:
-20℃避光保存。
注意事项:
JC-1如果一次使用量较小,需把每管再适当进行分装,尽量避免反复冻融。
JC-1在4℃、冰浴等较低温度情况下会凝固而粘在离心管管底、管壁或管盖内,可以20-25℃水浴温育片刻至全部融解后使用。
本产品仅限于专业人员的科学研究用,不得用于临床诊断或治疗,不得用于食品或药品,不得存放于 普通住宅内。
为了您的安全和健康,请穿实验服并戴一次性手套操作。
使用说明
使用说明:
JC-1用于检测细胞的线粒体膜电位时常用的浓度范围为1-20μg/ml,对于很多细胞适宜采用的JC-1浓度为10μg/ml。详细的使用方法请参考相关文献资料。
产品图片
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AUSTRALASIAN PLANT PATHOLOGY,2012,41(1),1-11.
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Schatten H, Sun QY.
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inhibiting fattyacid synthase.
PLoS One. 2012;7(3):e33376.
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Toxic effects of microcystin-LR on the HepG2 cell line under hypoxic and normoxic
conditions.
J Appl Toxicol.2012 Apr 27. doi: 10.1002/jat.2749. [Epub ahead of print].
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Gender segregation in gene expression and vulnerability to oxidative stress induced
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62.Su Y, Wang X, Xu W, Xue L, He C, Yang D, An R.
Arsenic trioxide increases the sensitivity of 786-0 renal carcinoma cells to
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Epub 2011 Dec 13.
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Salvianolic acid A protects human SH-SY5Y neuroblastoma cells against H2O2-induced
injury by increasing stress tolerance ability.
Biochem Biophys Res Commun. 2012 May 11;421(3):479-83.
doi: 10.1016/j.bbrc.2012.04.021.Epub 2012 Apr 9.
64.Shen X, Liu L, Yin F, Ma H, Zou S.
Effect of dehydroepiandrosterone on cell growth and mitochondrial function in TM-3
cells.
Gen Comp Endocrinol. 2012 May 15;177(1):177-86.
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Anti-benzopyrene-7,8-diol-9,10-epoxide induces apoptosis via mitochondrial pathway in
humanbronchiolar epithelium cells independent of the mitochondria permeability
transition pore.
Food Chem Toxicol. 2012 Jul;50(7):2417-23. doi: 10.1016/j.fct.2012.04.041.
Epub 2012 May 4.
66.Wang CQ, Zhang J, Sun YF, Wang D, Li CJ, Li WH, Lu C, Liu Z, Wu H, Hou XF, Chen C,
Zhou X
Detection of Neurotrophin-4 (NT-4) in Ejaculated Bull Spermatozoa and its Effect on
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Reprod Domest Anim. 2012 May 21. doi: 10.1111/j.1439-0531.2012.02048.x.
[Epub ahead of print]
67.Zhang J, Song W, Guo J, Zhang J, Sun Z, Ding F, Gao M.
Toxic effect of different ZnO particles on mouse alveolar macrophages.
J Hazard Mater.2012 Jun 15;219-220:148-55. doi: 10.1016/j.jhazmat.2012.03.069.
Epub 2012 Apr 3.
68.Zhao P, Han T, Guo JJ, Zhu SL, Wang J, Ao F, Jing MZ, She YL, Wu ZH, Ye LB
HCV NS4B induces apoptosis through the mitochondrial death pathway.
Virus Res.2012 Oct;169(1):1-7.doi:10.1016/j.virusres.2012.04.006.Epub 2012 Apr 19.
69.Li Z, Chen J, Lei T, Zhang H.
Tamoxifen induces apoptosis of mouse microglia cell line BV-2 cells via both
mitochondrial anddeath receptor pathways.
J Huazhong Univ Sci Technolog Med Sci. 2012 Apr;32(2):221-6.
70.Khan M, Ding C, Rasul A, Yi F, Li T, Gao H, Gao R, Zhong L, Zhang K, Fang X, Ma T
Isoalantolactone induces reactive oxygen species mediated apoptosis in pancreatic
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Int J Biol Sci. 2012;8(4):533-47. doi: 10.7150/ijbs.3753. Epub 2012 Mar 28.
71.Ding F, Shao ZW, Yang SH, Wu Q, Gao F, Xiong LM
Role of mitochondrial pathway in compression-induced apoptosis of nucleus pulposus
cells.
Apoptosis. 2012 Jun;17(6):579-90. doi: 10.1007/s10495-012-0708-3.
72.Lin CJ, Huang HC, Liu WJ, Jiang ZF.
Biomedical Imaging and Visualization Model of Mitochondrial Dysfunction and Oxidative
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Applied Mechanics and Materials,2012,1179-1182
.
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Mechanism of inhibition of P-glycoprotein mediated efflux by Pluronic P123/F127 block
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Eur J Pharm Biopharm. 2012 Oct 23. pii: S0939-6411(12)00312-8.
doi: 10.1016/j.ejpb.2012.09.014. [Epub ahead of print]
74.Ge H, Tollner TL, Hu Z, Da M, Li X, Guan H, Shan D, Lu J, Huang C, Dong Q.
Impaired mitochondrial function in murine oocytes is associated with controlled ovarian
hyperstimulation and invitro maturation.
Reprod Fertil Dev. 2012;24(7):945-52. doi: 10.1071/RD11212.
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Perfluorooctane sulfonate induces apoptosis in lung cancer A549 cells through reactive
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J Appl Toxicol. 2012 Sep 13. doi: 10.1002/jat.2785. [Epub ahead of print].
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The synthesis and biological evaluation of novel Danshensu-cysteine analog conjugates as
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77.Dai T, Zhao E, Lu G, Che K, He Q, Lu Y, Fang Q, Wang H, Zheng L, Li S, Huang C, Dong Q.
Sperm cryopreservation of yellow drum Nibea albiflora: A special emphasis on
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Aquaculture.Volumes 368–369, 24 November 2012, Pages 82–88.
78.Tu J, Wang T, Shi W, Wu G, Tian X, Wang Y, Ge D, Ren L.
Multifunctional ZnPc-loaded mesoporous silica nanoparticles for enhancement of
photodynamic therapy efficacyby endolysosomal escape.
Biomaterials. 2012 Nov;33(31):7903-14. doi: 10.1016/j.biomaterials.2012.07.025.
Epub 2012 Jul 26.
79.Zhang L, Sang H, Liu Y, Li J.
Manganese activates caspase-9-dependent apoptosis in human bronchial epithelial cells.
Hum Exp Toxicol. 2012 Dec 21. [Epub ahead of print]
80.Yuan L, Wang J, Xiao H, Xiao C, Wang Y, Liu X.
Isoorientin induces apoptosis through mitochondrial dysfunction and inhibition of
PI3K/Akt signaling pathway inHepG2 cancer cells.
Toxicol Appl Pharmacol. 2012 Nov 15;265(1):83-92. doi: 10.1016/j.taap.2012.09.022.
Epub 2012 Sep 28.
81.Li GQ, Chen XG, Wu XP, Xie JD, Liang YJ, Zhao XQ, Chen WQ, Fu LW.
Effect of dicycloplatin, a novel platinum chemotherapeutical drug, on inhibiting cell
growth and inducing cellapoptosis.
PLoS One. 2012;7(11):e48994. doi: 10.1371/journal.pone.0048994. Epub 2012 Nov 12.
82.Ma ZY, Qiao X, Xie CZ, Shao J, Xu JY, Qiang ZY, Lou JS.
Activities of a novel Schiff Base copper(II) complex on growth inhibition and apoptosis
induction toward MCF-7human breast cancer cells via mitochondrial pathway.
J Inorg Biochem. 2012 Dec;117:1-9. doi: 10.1016/j.jinorgbio.2012.08.007.
Epub 2012 Aug 24.
83.Lin F, Xu W, Guan C, Zhou M, Hong W, Fu L, Liu D, Xu A.
Niacin protects against UVB radiation-induced apoptosis in cultured human skin
keratinocytes.
Int J Mol Med. 2012 Apr;29(4):593-600. doi: 10.3892/ijmm.2012.886. Epub 2012 Jan 12.
84.Miao H, Zhao L, Li C, Shang Q, Lu H, Fu Z, Wang L, Jiang Y, Cao Y.
Inhibitory effect of Shikonin on Candida albicans growth.
Biol Pharm Bull. 2012;35(11):1956-63.
85.Shi CM, Wang YM, Zhang CM, Qiu J, Shen YH, Zhu JG, Chen L, Xu GF, Zhao YP, Ji CB,
Guo XR.
Knockdown of NYGGF4 (PID1) rescues insulin resistance and mitochondrial dysfunction
induced by FCCP in3T3-L1 adipocytes.
Mitochondrion.2012 Nov;12(6):600-6.doi:10.1016/j.mito.2012.10.008.Epub 2012 Oct 22.
86.Zhao X, Cong X, Zheng L, Xu L, Yin L, Peng J.
Dioscin, a natural steroid saponin, shows remarkable protective effect against
acetaminophen-induced liverdamage in vitro and in vivo.
Toxicol Lett. 2012 Oct 2;214(1):69-80. doi: 10.1016/j.toxlet.2012.08.005.
Epub 2012 Aug 21.
87.Ru Y, Yin L, Sun H, Yin S, Pan Q, Wei H, Wu L, Liu S.
A micropreparation of mitochondria from cells using magnetic beads with immunoaffinity.
Anal Biochem.2012 Feb 1;421(1):219-26.doi:10.1016/j.ab.2011.11.015.Epub 2011 Nov 23.
88.Shi CM, Xu GF, Yang L, Fu ZY, Chen L, Fu HL, Shen YH, Zhu L, Ji CB, Guo XR.
Overexpression of TFAM Protects 3T3-L1 Adipocytes from NYGGF4 (PID1) Overexpression-
Induced InsulinResistance and Mitochondrial Dysfunction.
Cell Biochem Biophys. 2012 Dec 30. [Epub ahead of print]
89.Liu Q, Yao JY, Qian C, Chen R, Li XY, Liu SW, Sun BG, Song LS, Hong J.
Effects of propofol on ischemia-induced ventricular arrhythmias and mitochondrial
ATP-sensitive potassium channels.
Acta Pharmacol Sin. 2012 Dec;33(12):1495-501. doi: 10.1038/aps.2012.86.
Epub 2012 Sep 17.
90.Chen XM, Liu J, Wang T, Shang J.
Colchicine-induced apoptosis in human normal liver L-02 cells by mitochondrial mediated
pathways.
Toxicol In Vitro.2012 Aug;26(5):649-55.doi:10.1016/j.tiv.2012.01.024.Epub 2012 Feb 8.
91.Zhu X, Chen C, Ye D, Guan D, Ye L, Jin J, Zhao H, Chen Y, Wang Z, Wang X, Xu Y.
Diammonium glycyrrhizinate upregulates PGC-1α and protects against Aβ1-42-induced
neurotoxicity.
PLoS One. 2012;7(4):e35823. doi: 10.1371/journal.pone.0035823. Epub 2012 Apr 23.
92.Zhang W, Huang Q, Hua Z.
Galangin and TRAIL cooperate to suppress A549 lung cancer proliferation via apoptosis
and p38 MAPK activation.
Acta Pharmaceutica Sinica B.Volume 2, Issue 6, December 2012, Pages 569–574.
93.Yue R, Hu H, Yiu KH, Luo T, Zhou Z, Xu L, Zhang S, Li K, Yu Z.
Lycopene protects against hypoxia/reoxygenation-induced apoptosis by preventing
mitochondrial dysfunction inprimary neonatal mouse cardiomyocytes.
PLoS One. 2012;7(11):e50778. doi: 10.1371/journal.pone.0050778. Epub 2012 Nov 30.
94.Gong Z, Yang L, Tang H, Pan R, Xie S, Guo L,Wang J, Deng Q, Xiong G, Xing Y,Dong J
Protective effects of curcumin against human immunodeficiency virus 1 gp120 V3
loop-induced
neuronal injury in rats.
NEURAL REGENERATION RESEARCH Volume 7, Issue 3, January 2012.
95.Lei JC, Yu JQ, Yin Y, Liu YW, Zou GL.
Alantolactone induces activation of apoptosis in human hepatoma cells.
Food Chem Toxicol. 2012 Sep;50(9):3313-9. doi: 10.1016/j.fct.2012.06.014.
Epub 2012 Jun 18.
96.Chen C, Han S, Liu W, Wang Y, Huang G.
Effect of vitrification on mitochondrial membrane potential in human metaphase II
oocytes.
J Assist Reprod Genet. 2012 Oct;29(10):1045-50. doi: 10.1007/s10815-012-9848-1.
Epub 2012 Aug 23.
97.Yu H, Li X, Sun S, Gao X, Zhou D.
c-Met inhibitor SU11274 enhances the response of the prostate cancer cell line DU145 to
ionizing radiation.
Biochem Biophys Res Commun. 2012 Oct 26;427(3):659-65.
doi:10.1016/j.bbrc.2012.09.117. Epub 2012 Sep 28.
98.Hu Y, Qi Y, Liu H, Fan G, Chai Y.
Effects of celastrol on human cervical cancer cells as revealed by ion-trap gas
chromatography-massspectrometry based metabolic profiling.
Biochim Biophys Acta. 2013 Mar;1830(3):2779-89.
99.Guo D, Bi H, Liu B, Wu Q, Wang D, Cui Y.
Reactive oxygen species-induced cytotoxic effects of zinc oxide nanoparticles in rat
retinal ganglion cells.
Toxicol In Vitro.2013 Mar;27(2):731-8.doi:10.1016/j.tiv.2012.12.001.Epub 2012 Dec 8.
100.Yue B, Zhang YS, Xu HM, Zhao CR, Li YY, Qin YZ, Wang RQ, Sun D, Yuan Y, Lou HX, Qu XJ.
Riccardin D-26, a synthesized macrocyclic bisbibenzyl compound, inhibits human
hepatocellular carcinoma growth through induction of apoptosis in p53-dependent way.
Cancer Lett. 2013 Jan 1;328(1):104-13. doi: 10.1016/j.canlet.2012.09.002.
Epub 2012 Sep 18.
101.Wang F, Gao Q, Guo S, Cheng J, Sun X, Li Q, Wang T, Zhang Z, Cao W, Tian Y.
The sonodynamic effect of curcumin on THP-1 cell-derived macrophages.
Biomed Res Int. 2013;2013:737264. doi: 10.1155/2013/737264. Epub 2012 Dec 30.
102.Pi J, Jin H, Liu R, Song B, Wu Q, Liu L, Jiang J, Yang F, Cai H, Cai J.
Pathway of cytotoxicity induced by folic acid modified selenium nanoparticles in MCF-7
cells.
Appl Microbiol Biotechnol. 2013 Feb;97(3):1051-62. doi: 10.1007/s00253-012-4359-7.
Epub 2012 Sep 4.
103.Song S, Wang S, Ma J, Yao L, Xing H, Zhang L, Liao L, Zhu D.
Biliverdin reductase/bilirubin mediates the anti-apoptotic effect of hypoxia in
pulmonary
arterial smooth musclecells through ERK1/2 pathway.
Exp Cell Res.2013 May 28.pii:S0014-4827(13)00221-8.doi:10.1016/j.yexcr.2013.05.015.
[Epub ahead of print]
104.Yang Y, Yan X, Duan W, Yan J, Yi W, Liang Z, Wang N, Li Y, Chen W, Yu S, Jin Z, Yi D.
Pterostilbene Exerts Antitumor Activity via the Notch1 Signaling Pathway in Human Lung
Adenocarcinoma Cells.
PLoS One. 2013 May 3;8(5):e62652. doi: 10.1371/journal.pone.0062652. Print 2013.
105.Liang D, Xiang L, Yang M, Zhang X, Guo B, Chen Y, Yang L, Cao J.
ZnT7 can protect MC3T3-E1 cells from oxidative stress-induced apoptosis via PI3K/Akt and
MAPK/ERK signalingpathways.
Cell Signal. 2013 May;25(5):1126-35. doi: 10.1016/j.cellsig.2013.02.003.
Epub 2013 Feb 10.
106.Fan Y, Wang C, Zhang Y, Hang P, Liu Y, Pan Z, Wang N, Du Z.
Genistein ameliorates adverse cardiac effects induced by arsenic trioxide through
preventing cardiomyocytesapoptosis.
Cell Physiol Biochem. 2013;31(1):80-91. doi: 10.1159/000343351. Epub 2013 Jan 22.
107.Sun S, Pan S, Miao A, Ling C, Pang S, Tang J, Chen D, Zhao C.
Active extracts of black tea (Camellia Sinensis) induce apoptosis of PC-3 prostate
cancer cells via mitochondrialdysfunction.
Oncol Rep. 2013 Aug;30(2):763-72. doi: 10.3892/or.2013.2504. Epub 2013 May 28.
108.Li P, Xue Y, Zhang W, Teng F, Sun Y, Qu T, Chen X, Cheng X, Song B, Luo W, Yu Q.
Sodium fluoride induces apoptosis in odontoblasts via a JNK-dependent mechanism.
Toxicology. 2013 Jun 7;308:138-45. doi: 10.1016/j.tox.2013.03.016. Epub 2013 Apr 8.
109.Liu Y, Wang L, Wu Y, Lv C, Li X, Cao X, Yang M, Feng D, Luo Z.
Pterostilbene exerts antitumor activity against human osteosarcoma cells by inhibiting
the JAK2/STAT3 signalingpathway.
Toxicology. 2013 Feb 8;304:120-31. doi: 10.1016/j.tox.2012.12.018. Epub 2013 Jan 8.
110.Tang Q, Li G, Wei X, Zhang J, Chiu JF, Hasenmayer D, Zhang D, Zhang H.
Resveratrol-induced apoptosis is enhanced by inhibition of autophagy in esophageal
squamous cell carcinoma.
Cancer Lett.2013 Mar 27.pii:S0304-3835(13)00251-6.doi:10.1016/j.canlet.2013.03.023.
[Epub ahead of print].
11`.Chen Y, Zhuang X, Xu Z, Lu L, Guo H, Wu W, Liao X.
Higenamine Combined with [6]-Gingerol Suppresses Doxorubicin-Triggered Oxidative Stress
and Apoptosis in Cardiomyocytes via Upregulation of PI3K/Akt Pathway.
Evidence-Based Complementary and Alternative Medicine.Volume 2013.
112.Ma J, Zhang L, Zhang J, Liu M, Wei L, Shen T, Ma C, Wang Y, Chen Y, Zhu D.
15-lipoxygenase-1/15-hydroxyeicosatetraenoic acid promotes hepatocellular cancer cells
growth through protein kinase B and heat shock protein 90 complex activation.
Int J Biochem Cell Biol. 2013 Jun;45(6):1031-41. doi: 10.1016/j.biocel.2013.02.018.
Epub 2013 Mar 6.
113.Cai B, Li X, Wang Y, Liu Y, Yang F, Chen H, Yin K, Tan X, Zhu J, Pan Z, Wang B, Lu Y.
Apoptosis of bone marrow mesenchymal stem cells caused by homocysteine via activating
JNK
signal.
PLoS One. 2013 May 7;8(5):e63561. doi: 10.1371/journal.pone.0063561. Print 2013.
114.Wu C, Wang C, Han T, Zhou X, Guo S, Zhang J.
Insight into the Cellular Internalization and Cytotoxicity of Graphene Quantum Dots.
Adv Healthc Mater. 2013 May 24. doi: 10.1002/adhm.201300066. [Epub ahead of print].
115.Ma LS, Jiang CY, Cui M, Lu R, Liu SS, Zheng BB, Li L, Li X.
Fluopsin C induces oncosis of human breast adenocarcinoma cells.
Acta Pharmacol Sin. 2013 May 27. doi: 10.1038/aps.2013.44. [Epub ahead of print].
116.Sun L, Zhao M, Yu XJ, Wang H, He X, Liu JK, Zang WJ.
Cardioprotection by acetylcholine: a novel mechanism via mitochondrial biogenesis and
function involving the PGC-1α pathway.
J Cell Physiol. 2013 Jun;228(6):1238-48. doi: 10.1002/jcp.24277.
117.Yuan F, Dong P, Wang X, Fu X, Dai M, Zhang W.
Toxicological effects of cigarette smoke on Ana-1 macrophages in vitro.
Exp Toxicol Pathol. 2013 Mar 18. pii: S0940-2993(13)00031-6.
doi: 10.1016/j.etp.2013.02.004. [Epub ahead of print]
118..Li T, Liu Z, Jiang K, Ruan Q.
Angiopoietin2 enhances doxorubin resistance in HepG2 cells by upregulating survivin and
Ref-1 via MSK1activation.
Cancer Lett.2013 May 2.pii:S0304-3835(13)00362-5.doi:10.1016/j.canlet.2013.04.028.
[Epub ahead of print].
119.Wu WY, Wang WY, Ma YL, Yan H, Wang XB, Qin YL, Su M, Chen T, Wang YP.
Sodium tanshinone IIA silate inhibits oxygen-glucose deprivation/recovery-induced
cardiomyocyte apoptosis viasuppression of the NF-κB/TNF-α pathway.
Br J Pharmacol. 2013 Jul;169(5):1058-71. doi: 10.1111/bph.12185.
120.Zheng J, Zhang Y, Xu W, Luo Y, Hao J, Shen XL, Yang X, Li X, Huang K.
Zinc protects HepG2 cells against the oxidative damage and DNA damage induced by
ochratoxin A.
Toxicol Appl Pharmacol. 2013 Apr 15;268(2):123-31. doi: 10.1016/j.taap.2013.01.021.
Epub 2013 Feb 4.
121.E Q, Liu X, Liu Y, Liu W, Zuo J.
Over-expression of GRP75 inhibits liver injury induced by oxidative damage.
Acta Biochim Biophys Sin (Shanghai). 2013 Feb;45(2):129-34.
122.Yi F, He X, Wang D.
Lycopene Protects Against MPP+-Induced Cytotoxicity by Maintaining Mitochondrial
Function
in SH-SY5Y Cells.
Neurochem Res. 2013 May 25. [Epub ahead of print]
123.Guo R, Liu B, Zhou S, Zhang B, Xu Y.
The protective effect of fasudil on the structure and function of cardiac mitochondria
from rats with type 2 diabetes induced by streptozotocin with a high-fat diet is
mediated by the attenuation of oxidative stress.
Biomed Res Int. 2013;2013:430791. doi: 10.1155/2013/430791. Epub 2013 May 22.
124.Li JW, Ning N, Ma YZ, Zhang R, Tan F, Chen NH.
Claulansine F suppresses apoptosis induced by sodium nitroprusside in PC12 cells.
Free Radic Res. 2013 Jul;47(6-7):488-97. doi: 10.3109/10715762.2013.770150.
Epub 2013 Apr 22.
125.Wang Q,X Cheng X,Zhang D, Gao X, Zhou L, Qin X, Xie G, Liu K, Qin Y, Liu B, Qin M.
Tectorigenin Attenuates Palmitate-Induced Endothelial Insulin Resistance via Targeting
ROS-Associated Inflammation and IRS-1 Pathway.
PLOS ONE.2013.
126.Jiang L, Liu Y, Ma MM, Tang YB, Zhou JG, Guan YY.
Mitochondria dependent pathway is involved in the protective effect of bestrophin-3 on
hydrogen peroxide-induced apoptosis in basilar artery smooth muscle cells.
Apoptosis. 2013 May;18(5):556-65. doi: 10.1007/s10495-013-0828-4.
127.Huang H, Wu K, You Q, Huang R, Li S, Wu K.
Naringin inhibits high glucose-induced cardiomyocyte apoptosis by attenuating
mitochondrial dysfunction andmodulating the activation of the p38 signaling pathway.
Int J Mol Med. 2013 Jun 3. doi: 10.3892/ijmm.2013.1403. [Epub ahead of print]
128.Zhou D, Wei A, Cao C, Ruan J.
DICO, a novel nonaromatic B-ring flavonoid, induces G2/M cell cycle arrest and apoptosis
in human hepatomacells.
Food Chem Toxicol.2013 Jul;57:322-9.doi:10.1016/j.fct.2013.03.032.Epub 2013 Apr 6.
129.Luo CL, Chen XP, Li LL, Li QQ, Li BX, Xue AM, Xu HF, Dai DK, Shen YW, Tao LY, Zhao ZQ.
Poloxamer 188 attenuates in vitro traumatic brain injury-induced mitochondrial and
lysosomal membranepermeabilization damage in cultured primary neurons.
J Neurotrauma. 2013 Apr 1;30(7):597-607. doi: 10.1089/neu.2012.2425.
130.Li X, Tao H, Xie K, Ni Z, Yan Y, Wei K, Chuang PY, He JC, Gu L.
cAMP signaling prevents podocyte apoptosis via activation of protein kinase A and
mitochondrial fusion.
PLoS One. 2014 Mar 18;9(3):e92003. doi: 10.1371/journal.pone.0092003. eCollection
2014.
131.Sun J, Bai S, Bai W, Zou F, Zhang L, Li G, Hu Y, Li M, Yan R, Su Z, Huang Y.
1,3-Dichloro-2-propanol inhibits progesterone production through the expression of
steroidogenic enzymes and cAMP concentration in Leydig cells.
Food Chem. 2014 Jul 1;154:330-6. doi: 10.1016/j.foodchem.2014.01.017. Epub 2014 Jan
14.
132.Chang C, Wu G, Gao P, Yang L, Liu W, Zuo J.
Upregulated Parkin expression protects mitochondrial homeostasis in DJ-1 konckdown cells
and cells overexpressing the DJ-1 L166P mutation.
Mol Cell Biochem. 2014 Feb;387(1-2):187-95. doi: 10.1007/s11010-013-1884-3. Epub 2013
Nov 16.
133.Yang L, Di G, Qi X, Qu M, Wang Y, Duan H, Danielson P, Xie L, Zhou Q.
Substance P promotes diabetic corneal epithelial wound healing through molecular
mechanisms mediated via the neurokinin-1 receptor.
Diabetes. 2014 Jul 9. pii: DB_140163.
134.Li D, Ye Y, Lin S, Deng L, Fan X, Zhang Y, Deng X, Li Y, Yan H, Ma Y.
Evaluation of deoxynivalenol-induced toxic effects on DF-1 cells in vitro: cell-cycle
arrest, oxidative stress, and apoptosis.
Environ Toxicol Pharmacol. 2014 Jan;37(1):141-9. doi: 10.1016/j.etap.2013.11.015.
Epub 2013 Nov 26.
135.He M, Dong C, Xie Y, Li J, Yuan D, Bai Y, Shao C.
Reciprocal bystander effect between α-irradiated macrophage and hepatocyte is mediated
by cAMP through a membrane signaling pathway.
Mutat Res Fundam Mol Mech Mutagen. 2014 Mar 20;763-764C:1-9. doi: 10.1016/
j.mrfmmm.2014.03.001.
136.Pan HY, Yang H, Shao MY, Xu J, Zhang P, Cheng R, Hu T.
Sphingosine-1-phosphate mediates AKT/ERK maintenance of dental pulp homoeostasis.
Int Endod J. 2014 Jun 16. doi: 10.1111/iej.12335.
137.Chu JH, Zhao CR, Song ZY, Wang RQ, Qin YZ, Li WB, Qu XJ.
1082-39, an analogue of sorafenib, inhibited human cancer cell growth more potently than
sorafenib.
Biomed Pharmacother. 2014 Apr;68(3):335-41. doi: 10.1016/j.biopha.2014.01.010. Epub
2014 Feb 7.
138.Sun ZB, Wang JW, Xiao H, Zhang QS, Kan WS, Mo FB, Hu S, Ye SN.
Icariin may benefit the mesenchymal stem cells of patients with steroid-associated
osteonecrosis by ABCB1-promoter demethylation: a preliminary study.
Osteoporos Int. 2014 Aug 12.
139.Zheng L, Sun X, Zhu X, Lv F, Zhong Z, Zhang F, Guo W, Cao W, Yang L, Tian Y.
Apoptosis of THP-1 derived macrophages induced by sonodynamic therapy using a new
sonosensitizer hydroxyl acetylated curcumin.
PLoS One. 2014 Mar 27;9(3):e93133. doi: 10.1371/journal.pone.0093133. eCollection
2014.
140.Cui SX, Zhang HL, Xu WF, Qu XJ.
13F-1, a novel 5-fluorouracil prodrug containing an Asn-Gly-Arg (NO2) COOCH3 tripeptide,
inhibits human colonic carcinoma growth by targeting Aminopeptidase N (APN/CD13).
Eur J Pharmacol. 2014 Jul 5;734:50-9. doi: 10.1016/j.ejphar.2014.04.001. Epub 2014
Apr 13.
141.Fang L, Bai C, Chen Y, Dai J, Xiang Y, Ji X, Huang C, Dong Q.
Inhibition of ROS production through mitochondria-targeted antioxidant and mitochondrial
uncoupling increases post-thaw sperm viability in yellow catfish.
Cryobiology. 2014 Sep 27. pii: S0011-2240(14)00249-1. doi: 10.1016/
j.cryobiol.2014.09.005.
142.Wang C, Xia W, Jiang Q, Xu Y, Yu P.
Differential effects of lipid fractions from silver carp brain on human cervical
carcinoma cells in vitro.
Food Funct. 2014 Sep;5(9):2194-201. doi: 10.1039/c4fo00168k.
143.Fan S, Li X, Lin J, Chen S, Shan J, Qi G.
Honokiol inhibits tumor necrosis factor-α-stimulated rat aortic smooth muscle cell
proliferation via caspase- and mitochondrial-dependent apoptosis.
Inflammation. 2014 Feb;37(1):17-26. doi: 10.1007/s10753-013-9707-y.
144.Guo P, Pi H, Xu S, Zhang L, Li Y, Li M, Cao Z, Tian L, Xie J, Li R, He M, Lu Y, Liu C,
Duan W, Yu Z, Zhou Z.
Melatonin Improves Mitochondrial Function by Promoting MT1/SIRT1/PGC-1 Alpha-Dependent
Mitochondrial Biogenesis in Cadmium-Induced Hepatotoxicity In Vitro.
Toxicol Sci. 2014 Aug 26. pii: kfu164.
145.Li D, Ma H, Ye Y, Ji C, Tang X, Ouyang D, Chen J, Li Y, Ma Y.
Deoxynivalenol induces apoptosis in mouse thymic epithelial cells through mitochondria-
mediated pathway.
Environ Toxicol Pharmacol. 2014 Jul;38(1):163-71. doi: 10.1016/j.etap.2014.05.015.
Epub 2014 Jun 4.
146.Liu L, Li T, Tan J, Fu J, Guo Q, Ji H, Zhang Y.
NG as a novel nitric oxide donor induces apoptosis by increasing reactive oxygen species
and inhibiting mitochondrial function in MGC803 cells.
Int Immunopharmacol. 2014 Aug 16;23(1):27-36. doi: 10.1016/j.intimp.2014.08.005.
147.Zhang X, Yu Q, Jiang W, Bi Y, Zhang Y, Gong M, Wei X, Li T, Chen J.
All-trans retinoic acid suppresses apoptosis in PC12 cells injured by oxygen and glucose
deprivation via the retinoic acid receptor α signaling pathway.
Mol Med Rep. 2014 Nov;10(5):2549-55. doi: 10.3892/mmr.2014.2568. Epub 2014 Sep 15.
148.Jiang L, Zhao MN, Liu TY, Wu XS, Weng H, Ding Q, Shu YJ, Bao RF, Li ML, Mu JS, Wu WG,
Ding QC, Cao Y, Hu YP, Shen BY, Tan ZJ, Liu YB.
Bufalin induces cell cycle arrest and apoptosis in gallbladder carcinoma cells.
Tumour Biol. 2014 Aug 2.
149.Tang C, Liang J, Qian J, Jin L, Du M, Li M, Li D.
Opposing role of JNK-p38 kinase and ERK1/2 in hydrogen peroxide-induced oxidative damage
of human trophoblast-like JEG-3 cells.
Int J Clin Exp Pathol. 2014 Feb 15;7(3):959-68. eCollection 2014.
150.Pan H, Cheng L, Yang H, Zou W, Cheng R, Hu T.
Lysophosphatidic acid rescues human dental pulp cells from ischemia-induced apoptosis.
J Endod. 2014 Feb;40(2):217-22. doi: 10.1016/j.joen.2013.07.015. Epub 2013 Sep 4.
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