使用说明：
1. BAY 11-7082常见使用浓度范围为1-100μM。具体的最佳工作浓度请参考相关文献，或根据实验目的，以
   及所培养的特定细胞和组织，通过实验进行摸索和优化。

使用本产品的文献：
1. Wang LY, Wang HY, Ouyang J, Yu L, Chen B, Qin JQ, Qiu XZ.
   Low concentration of lipopolysaccharide acts on MC3T3-E1 osteoblasts and induces
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   Uric acid increases fibronectin synthesis through upregulation of lysyl oxidase
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3. Dong Z, An F, Wu T, Zhang C, Zhang M, Zhang Y, An G, An F.
   PTX3, a key component of innate immunity, is induced by SAA via FPRL1-mediated
   signaling inHAECs.
   J Cell Biochem. 2011 Aug;112(8):2097-105.
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   Methyl-1-hydroxy-2-naphthoate, a novel naphthol derivative, inhibits
   lipopolysaccharide-inducedinflammatory response in macrophages via suppression of
   NF-κB, JNK and p38 MAPK pathways.
   Inflamm Res. 2011 Sep;60(9):851-9.
5. Chen J, Jiang H, Yang J, Chen SS, Xu L.
   Down-regulation of CREB-binding protein expression blocks thrombin-mediated
   endothelial activation by inhibiting acetylation of NF-κB.
   Int J Cardiol. 2012 Jan 26;154(2):147-52.
6. Lu Y, Liu A, Zhou X, Kouadir M, Zhao W, Zhang S, Yin X, Yang L, Zhao D.
   Prion peptide PrP106-126 induces inducible nitric oxide synthase and proinflammatory
   cytokinegene expression through the activation of NF-κB in macrophage cells.
   DNA Cell Biol. 2012 May;31(5):833-8.
7. Wang QS, Xiang Y, Cui YL, Lin KM, Zhang XF.
   Dietary blue pigments derived from genipin, attenuate inflammation by inhibiting LPS-
   inducediNOS and COX-2 expression via the NF-κB inactivation.
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8. Zhu F, Shen F, Fan Y, Xie Y, Xia Y, Kong Y.
   Osteopontin increases the expression of β1, 4-Galactosyltransferase-I and promotes
   adhesion inhuman RL95-2 cells.
   Glycoconj J. 2012 Jul 31.
9. Wang QS, Cui YL, Dong TJ, Zhang XF, Lin KM.
   Ethanol extract from a Chinese herbal formula, "Zuojin Pill", inhibit the expression
   of inflammatorymediators in lipopolysaccharide-stimulated RAW 264.7 mouse macrophages.
   J Ethnopharmacol. 2012 May 7;141(1):377-85. Epub 2012 Mar 6.
10.Dong X, Yu LG, Sun R, Cheng YN, Cao H, Yang KM, Dong YN, Wu Y, Guo XL.
   Inhibition of PTEN expression and activity by angiotensin II induces proliferation and
   migration ofvascular smooth muscle cells.
   J Cell Biochem. 2012 Aug 8.
11.Chen X, Ren F, Hesketh J, Shi X, Li J, Gan F, Huang K.
   Reactive oxygen species regulate the replication of porcine circovirus type 2 via NF-κB
   pathway.
   Virology. 2012 Apr 25;426(1):66-72.
12.Ni XQ, Zhu JH, Yao NH, Qian J, Yang XJ.
   Statins suppress glucose-induced plasminogen activator inhibitor-1 expression by
   regulating RhoA and nuclear factor-κB activities in cardiac microvascular endothelial
   cells.
   Exp Biol Med (Maywood). 2013 Jan 1;238(1):37-46. doi: 10.1258/ebm.2012.012127.
13.Zhu W, Ma H, Miao J, Huang G, Tong M, Zou S.
   β-Glucan modulates the lipopolysaccharide-induced innate immune response in rat mammary
   epithelial cells.
   Int Immunopharmacol. 2013 Feb;15(2):457-65. doi: 10.1016/j.intimp.2012.12.007.
   Epub 2012 Dec 20.
14.Zhao Y, Xu Y, Li Y, Xu W, Luo F, Wang B, Pang Y, Xiang Q, Zhou J, Wang X, Liu Q.
   NF-κB-mediated inflammation leading to EMT via miR-200c is involved in cell
   transformation induced by cigarettesmoke extract.
   Toxicol Sci. 2013 Jul 3.
15.Qiu M, Chen Y, Chu Y, Song S, Yang N, Gao J, Wu Z.
   Zinc ionophores pyrithione inhibits herpes simplex virus replication through interfering
   with proteasome functionand NF-κB activation.
   ntiviral Res. 2013 Jul 15. pii: S0166-3542(13)00188-5. doi: 10.1016/j.antiviral.
   2013.07.001.
16.Wang J, Niu Z, Shi Y, Gao C, Wang X, Han J, Li J, Gao Z, Zhu X, Song X, Qin Z, Wang H.
   Bcl-3, induced by Tax and HTLV-1, inhibits NF-κB activation and promotes autophagy.
   Cell Signal. 2013 Dec;25(12):2797-804. doi: 10.1016/j.cellsig.2013.09.010. Epub 2013
   Sep 14.
17.Gan X, Chen B, Shen Z, Liu Y, Li H, Xie X, Xu X, Li H, Huang Z, Chen J.
   High GPX1 expression promotes esophageal squamous cell carcinoma invasion, migration,
   proliferation and cisplatin-resistance but can be reduced by vitamin D.
   Int J Clin Exp Med. 2014 Sep 15;7(9):2530-40. eCollection 2014.
18.Sun H, Wu Y, Fu D, Liu Y, Huang C.
   SIRT6 regulates osteogenic differentiation of rat bone marrow mesenchymal stem cells
   partially via suppressing the nuclear factor-κB signaling pathway.
   Stem Cells. 2014 Jul;32(7):1943-55. doi: 10.1002/stem.1671.
19.Zhao W, Zhou X, Lu Y, Peng Y, Lin Z, Lin J, Yang L, Yin X, Zhao D.
   Mycobacterium bovis ornithine carbamoyltransferase, MB1684, induces proinflammatory
   cytokine gene expression by activating NF-κB in macrophages.
   DNA Cell Biol. 2014 May;33(5):311-9. doi: 10.1089/dna.2013.2026. Epub 2014 Feb 25.
20.Liu S, Wu D, Li L, Sun X, Xie W, Li X.
   NF-κB activation was involved in reactive oxygen species-mediated apoptosis and
   autophagy in 1-oxoeudesm-11(13)-eno-12,8α-lactone-treated human lung cancer cells.
   Arch Pharm Res. 2014 Aug;37(8):1039-52. doi: 10.1007/s12272-013-0270-8. Epub 2013 Nov
   6.
21.Shen S, Guo J, Luo Y, Zhang W, Cui Y, Wang Q, Zhang Z, Wang T.
   Functional proteomics revealed IL-1β amplifies TNF downstream protein signals in human
   synoviocytes in a TNF-independent manner.
   Biochem Biophys Res Commun. 2014 Jul 18;450(1):538-44. doi: 10.1016/j.bbrc.
   2014.06.008. Epub 2014 Jun 10.
22.Dang Y, Xu Y, Wu W, Li W, Sun Y, Yang J, Zhu Y, Zhang C.
   Tetrandrine suppresses lipopolysaccharide-induced microglial activation by inhibiting
   NF-κB and ERK signaling pathways in BV2 cells.
   PLoS One. 2014 Aug 12;9(8):e102522. doi: 10.1371/journal.pone.0102522. eCollection
   2014.
23.Wang H, Wang X, Li X, Fan Y, Li G, Guo C, Zhu F, Zhang L, Shi Y.
   CD68(+)HLA-DR(+) M1-like macrophages promote motility of HCC cells via NF-κB/FAK
   pathway.
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   11.
24.Zhang Y, Zhang X, Qu S.
   Ceftriaxone Protects Astrocytes from MPP+ via Suppression of NF-κB/JNK/c-Jun Signaling.
   Mol Neurobiol. 2014 Aug 12.
25.Hu WT, Li MQ, Liu W, Jin LP, Li DJ, Zhu XY.
   IL-33 enhances proliferation and invasiveness of decidual stromal cells by up-regulation
   of CCL2/CCR2 via NF-κB and ERK1/2 signaling.
   Mol Hum Reprod. 2014 Apr;20(4):358-72. doi: 10.1093/molehr/gat094. Epub 2013 Dec 15.