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产品简介
产品简介：
| 产品编号 | 产品名称 | 产品包装 | 产品价格 |
| S1748 | MG-132(Proteasome抑制剂) | 1mg | 286.00元 |
MG-132也写作MG132，也称Z-LLL-CHO，Z-Leu-Leu-Leu-CHO，Z-Leu-Leu-Leu-al或Carbobenzoxy-L-leucyl-L-leucyl-L-leucinal，是一种常用的Proteasome抑制剂，即蛋白酶体抑制剂。MG-132可以通透细胞，选择性抑制Proteasome，Ki＝4nM。可以激活JNK1并抑制NF-κB的激活(IC50=3μM)。在10μM时可以诱导PC12细胞产生neurite outgrowth。
MG-132分子量为475.62，分子式为C26H41N3O5，CAS Number：133407-82-6。本产品纯度大于99%。
本MG-132为进口分装，用DMSO配制，浓度为20mg/ml，共50μl。
包装清单：
产品编号 |
产品名称 |
包装 |
S1748 |
MG-132(Proteasome抑制剂, 20mg/ml) |
1mg |
— |
说明书 |
1份 |
保存条件：
-20℃避光保存，半年有效。
注意事项：
本MG-132在4℃、冰浴等较低温度情况下会凝固而粘在离心管管底、管壁或管盖内，可以20-25℃水浴温育片刻至全部融解后使用。
为了您的安全和健康，请穿实验服并戴一次性手套操作。
使用说明
使用说明：
1. MG-132常见使用浓度范围为1-50μM。具体的最佳工作浓度请参考相关文献，或根据实验目的，以及所培
养的特定细胞和组织，通过实验进行摸索和优化。
产品图片
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Identification and preliminary functional analysis of alternative splicing of Siah1 in
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9. Chen HY, Ren XY, Wang WH, Zhang YX, Chen SF, Zhang B, Wang LX.
Upregulated ROS production induced by the proteasome inhibitor MG-132 on XBP1 gene
expression and cell apoptosis in Tca-8113 cells.
Biomed Pharmacother. 2014 Jul;68(6):709-13. doi: 10.1016/j.biopha.2014.07.011. Epub
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Inflammatory modulation effect of glycopeptide from Ganoderma capense (Lloyd) Teng.
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PDK4 protein promotes tumorigenesis through activation of cAMP-response element-binding
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27.
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