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MG-132(Proteasome抑制剂) |
产品编号: S1748
产品包装: 1mg
产品价格: 286.00元 |
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产品简介
产品简介:
MG-132也写作MG132,也称Z-LLL-CHO,Z-Leu-Leu-Leu-CHO,Z-Leu-Leu-Leu-al或Carbobenzoxy-L-leucyl-L-leucyl-L-leucinal,是一种常用的Proteasome抑制剂,即蛋白酶体抑制剂。MG-132可以通透细胞,选择性抑制Proteasome,Ki=4nM。可以激活JNK1并抑制NF-κB的激活(IC50=3μM)。在10μM时可以诱导PC12细胞产生neurite outgrowth。
MG-132分子量为475.62,分子式为C26H41N3O5,CAS Number:133407-82-6。本产品纯度大于99%。
本MG-132为进口分装,用DMSO配制,浓度为20mg/ml,共50μl。
包装清单:
产品编号 |
产品名称 |
包装 |
S1748 |
MG-132(Proteasome抑制剂, 20mg/ml) |
1mg |
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说明书 |
1份 |
保存条件:
-20℃避光保存,半年有效。
注意事项:
本MG-132在4℃、冰浴等较低温度情况下会凝固而粘在离心管管底、管壁或管盖内,可以20-25℃水浴温育片刻至全部融解后使用。
为了您的安全和健康,请穿实验服并戴一次性手套操作。
使用说明
使用说明:
1. MG-132常见使用浓度范围为1-50μM。具体的最佳工作浓度请参考相关文献,或根据实验目的,以及所培
养的特定细胞和组织,通过实验进行摸索和优化。
产品图片
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相关论文
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1. Wu H, Chen Y, Wang ZY, Li W, Li JQ, Zhang L, Lu YJ.
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Identification and preliminary functional analysis of alternative splicing of Siah1 in
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9. Chen HY, Ren XY, Wang WH, Zhang YX, Chen SF, Zhang B, Wang LX.
Upregulated ROS production induced by the proteasome inhibitor MG-132 on XBP1 gene
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Inflammatory modulation effect of glycopeptide from Ganoderma capense (Lloyd) Teng.
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PDK4 protein promotes tumorigenesis through activation of cAMP-response element-binding
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27.
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